KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD4
All Species:
45.15
Human Site:
S223
Identified Species:
90.3
UniProt:
P55036
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55036
NP_002801.1
377
40737
S223
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
NP_001130040
377
40717
S223
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35226
376
40685
S223
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Rat
Rattus norvegicus
NP_112621
380
41055
S223
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001135862
376
40515
S223
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Frog
Xenopus laevis
NP_001084296
376
40546
S223
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Zebra Danio
Brachydanio rerio
NP_001002112
372
40106
S223
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P55035
396
42600
S224
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Honey Bee
Apis mellifera
XP_393112
399
43959
S223
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_801754
391
42345
S227
L
A
M
A
L
R
I
S
M
E
E
Q
R
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P55034
386
40739
S233
L
A
L
A
L
R
V
S
M
E
E
E
R
A
R
Baker's Yeast
Sacchar. cerevisiae
P38886
268
29729
K130
D
E
L
I
R
L
A
K
T
L
K
K
N
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
N.A.
N.A.
96
97.8
N.A.
N.A.
94.9
91.2
85.4
N.A.
57.8
61.1
N.A.
61.1
Protein Similarity:
100
N.A.
100
N.A.
N.A.
97.6
98.1
N.A.
N.A.
98.1
95.2
91.5
N.A.
71.9
71.9
N.A.
75.4
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
100
N.A.
86.6
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
100
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.9
33.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
86.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
92
0
92
0
0
9
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
92
92
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
9
9
0
0
0
% K
% Leu:
92
0
92
0
92
9
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
92
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
84
0
84
0
% Q
% Arg:
0
0
0
0
9
92
0
0
0
0
0
0
92
0
92
% R
% Ser:
0
0
0
0
0
0
0
92
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
84
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _