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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD4
All Species:
25.15
Human Site:
S280
Identified Species:
50.3
UniProt:
P55036
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55036
NP_002801.1
377
40737
S280
T
G
L
P
D
L
S
S
M
T
E
E
E
Q
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
NP_001130040
377
40717
S280
T
G
L
P
D
L
S
S
M
T
E
E
E
Q
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35226
376
40685
S280
P
G
L
P
D
L
S
S
M
T
E
E
E
Q
I
Rat
Rattus norvegicus
NP_112621
380
41055
S283
A
G
L
P
D
L
S
S
M
T
E
E
E
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001135862
376
40515
S280
A
G
L
P
D
L
S
S
M
T
E
E
E
Q
I
Frog
Xenopus laevis
NP_001084296
376
40546
S280
S
G
L
P
D
F
S
S
M
T
E
D
E
Q
I
Zebra Danio
Brachydanio rerio
NP_001002112
372
40106
S280
A
A
L
P
D
F
S
S
M
T
E
E
E
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P55035
396
42600
N301
D
N
L
P
D
F
A
N
M
T
E
E
E
Q
I
Honey Bee
Apis mellifera
XP_393112
399
43959
P285
S
T
A
D
N
T
V
P
A
N
I
N
A
P
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_801754
391
42345
A286
T
P
T
P
D
L
G
A
M
T
E
E
E
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P55034
386
40739
L286
P
M
D
E
D
S
A
L
L
D
Q
A
I
A
M
Baker's Yeast
Sacchar. cerevisiae
P38886
268
29729
E183
P
G
P
R
L
L
Y
E
N
I
A
S
S
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
N.A.
N.A.
96
97.8
N.A.
N.A.
94.9
91.2
85.4
N.A.
57.8
61.1
N.A.
61.1
Protein Similarity:
100
N.A.
100
N.A.
N.A.
97.6
98.1
N.A.
N.A.
98.1
95.2
91.5
N.A.
71.9
71.9
N.A.
75.4
P-Site Identity:
100
N.A.
100
N.A.
N.A.
93.3
93.3
N.A.
N.A.
93.3
80
80
N.A.
66.6
0
N.A.
73.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
80
N.A.
80
13.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.9
33.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
9
9
0
0
0
17
9
9
0
9
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
9
84
0
0
0
0
9
0
9
0
0
9
% D
% Glu:
0
0
0
9
0
0
0
9
0
0
75
67
75
0
0
% E
% Phe:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
59
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
9
0
9
0
84
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
67
0
9
59
0
9
9
0
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
75
0
0
0
0
0
9
% M
% Asn:
0
9
0
0
9
0
0
9
9
9
0
9
0
0
0
% N
% Pro:
25
9
9
75
0
0
0
9
0
0
0
0
0
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
75
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
0
0
0
0
9
59
59
0
0
0
9
9
0
0
% S
% Thr:
25
9
9
0
0
9
0
0
0
75
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _