KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD4
All Species:
26.97
Human Site:
T264
Identified Species:
53.94
UniProt:
P55036
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55036
NP_002801.1
377
40737
T264
D
D
A
L
L
K
M
T
I
S
Q
Q
E
F
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
NP_001130040
377
40717
T264
D
D
A
L
L
K
M
T
I
S
Q
Q
E
F
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35226
376
40685
T264
D
D
A
L
L
K
M
T
I
N
Q
Q
E
F
G
Rat
Rattus norvegicus
NP_112621
380
41055
T267
D
D
A
L
L
K
M
T
I
S
Q
Q
E
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001135862
376
40515
T264
D
D
A
L
L
K
M
T
I
T
Q
Q
E
F
G
Frog
Xenopus laevis
NP_001084296
376
40546
T264
D
E
A
L
L
K
M
T
I
G
Q
Q
E
G
T
Zebra Danio
Brachydanio rerio
NP_001002112
372
40106
S264
E
E
A
L
L
K
M
S
A
S
Q
P
E
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P55035
396
42600
L285
E
A
M
L
Q
R
A
L
A
L
S
T
E
T
P
Honey Bee
Apis mellifera
XP_393112
399
43959
S269
L
K
R
A
L
A
M
S
L
E
G
A
E
T
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_801754
391
42345
N270
E
Q
A
L
V
M
S
N
Q
P
M
S
S
F
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P55034
386
40739
A270
S
A
S
Q
E
T
V
A
R
T
T
D
K
N
A
Baker's Yeast
Sacchar. cerevisiae
P38886
268
29729
E167
A
V
N
N
P
Q
E
E
T
S
H
L
L
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
N.A.
N.A.
96
97.8
N.A.
N.A.
94.9
91.2
85.4
N.A.
57.8
61.1
N.A.
61.1
Protein Similarity:
100
N.A.
100
N.A.
N.A.
97.6
98.1
N.A.
N.A.
98.1
95.2
91.5
N.A.
71.9
71.9
N.A.
75.4
P-Site Identity:
100
N.A.
100
N.A.
N.A.
93.3
100
N.A.
N.A.
93.3
73.3
60
N.A.
13.3
20
N.A.
20
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
N.A.
100
80
80
N.A.
26.6
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.9
33.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
67
9
0
9
9
9
17
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
42
0
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
25
17
0
0
9
0
9
9
0
9
0
0
75
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
9
0
0
9
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
59
0
0
0
0
0
0
9
0
0
% K
% Leu:
9
0
0
75
67
0
0
9
9
9
0
9
9
0
0
% L
% Met:
0
0
9
0
0
9
67
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
9
0
9
0
0
0
9
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
9
0
9
0
0
9
% P
% Gln:
0
9
0
9
9
9
0
0
9
0
59
50
0
0
0
% Q
% Arg:
0
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% R
% Ser:
9
0
9
0
0
0
9
17
0
42
9
9
9
9
9
% S
% Thr:
0
0
0
0
0
9
0
50
9
17
9
9
0
25
9
% T
% Val:
0
9
0
0
9
0
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _