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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD4
All Species:
20.91
Human Site:
Y326
Identified Species:
41.82
UniProt:
P55036
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55036
NP_002801.1
377
40737
Y326
P
A
K
E
E
D
D
Y
D
V
M
Q
D
P
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
NP_001130040
377
40717
Y326
P
A
K
E
E
D
D
Y
D
V
M
Q
D
P
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35226
376
40685
D326
V
K
E
E
D
D
Y
D
V
M
Q
D
P
E
F
Rat
Rattus norvegicus
NP_112621
380
41055
Y329
P
V
K
E
E
D
D
Y
D
V
M
Q
D
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001135862
376
40515
Y326
P
T
K
E
E
D
D
Y
D
V
M
Q
D
P
E
Frog
Xenopus laevis
NP_001084296
376
40546
Y326
P
A
K
E
E
D
D
Y
D
V
M
Q
D
P
E
Zebra Danio
Brachydanio rerio
NP_001002112
372
40106
D326
D
D
Y
D
V
M
Q
D
P
E
F
L
Q
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P55035
396
42600
S347
M
D
V
D
E
D
Y
S
E
V
I
G
D
P
A
Honey Bee
Apis mellifera
XP_393112
399
43959
A331
M
E
V
E
E
D
Y
A
A
V
M
S
D
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_801754
391
42345
S332
T
D
T
P
A
T
D
S
A
A
S
K
P
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P55034
386
40739
N332
E
A
T
G
A
G
N
N
L
L
G
N
Q
A
F
Baker's Yeast
Sacchar. cerevisiae
P38886
268
29729
A229
P
S
M
D
P
E
L
A
M
A
L
R
L
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
N.A.
N.A.
96
97.8
N.A.
N.A.
94.9
91.2
85.4
N.A.
57.8
61.1
N.A.
61.1
Protein Similarity:
100
N.A.
100
N.A.
N.A.
97.6
98.1
N.A.
N.A.
98.1
95.2
91.5
N.A.
71.9
71.9
N.A.
75.4
P-Site Identity:
100
N.A.
100
N.A.
N.A.
13.3
93.3
N.A.
N.A.
93.3
100
0
N.A.
33.3
46.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
33.3
93.3
N.A.
N.A.
93.3
100
6.6
N.A.
53.3
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.9
33.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
17
0
0
17
17
17
0
0
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
25
0
25
9
67
50
17
42
0
0
9
59
9
9
% D
% Glu:
9
9
9
59
59
9
0
0
9
9
0
0
0
9
42
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
17
% F
% Gly:
0
0
0
9
0
9
0
0
0
0
9
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
9
42
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
0
0
9
0
9
9
9
9
9
0
0
% L
% Met:
17
0
9
0
0
9
0
0
9
9
50
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
9
9
0
0
0
9
0
0
0
% N
% Pro:
50
0
0
9
9
0
0
0
9
0
0
0
17
59
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
9
42
17
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
9
0
0
0
0
0
17
0
0
9
9
0
17
0
% S
% Thr:
9
9
17
0
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
9
9
17
0
9
0
0
0
9
59
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
25
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _