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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRG2
All Species:
40.91
Human Site:
S224
Identified Species:
64.29
UniProt:
P55039
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55039
NP_001379.1
364
40746
S224
V
L
F
R
E
D
C
S
P
D
E
F
I
D
V
Chimpanzee
Pan troglodytes
XP_001158439
343
38111
L207
E
K
L
V
Q
L
I
L
H
E
Y
K
I
F
N
Rhesus Macaque
Macaca mulatta
XP_001093452
343
38083
L207
E
K
L
V
Q
L
I
L
H
E
Y
K
I
F
N
Dog
Lupus familis
XP_536661
364
40714
S224
V
L
F
R
E
D
C
S
P
D
E
F
I
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXB9
364
40700
S224
V
L
F
R
E
D
C
S
P
D
D
F
I
D
V
Rat
Rattus norvegicus
XP_001076012
364
40701
S224
V
L
F
R
E
D
C
S
P
D
D
F
I
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512784
296
33355
I161
D
C
S
P
D
E
F
I
D
V
I
V
G
N
R
Chicken
Gallus gallus
NP_001025805
364
40687
S224
V
L
F
R
E
D
C
S
P
D
E
F
I
D
V
Frog
Xenopus laevis
P43690
367
40396
T226
I
T
L
R
S
D
A
T
A
D
D
L
I
D
V
Zebra Danio
Brachydanio rerio
NP_997803
364
40863
S224
V
L
F
R
E
D
C
S
P
D
D
F
I
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32234
368
41113
T226
I
T
L
R
Y
D
A
T
S
D
D
L
I
D
V
Honey Bee
Apis mellifera
XP_624466
363
40827
S223
V
L
F
R
E
D
C
S
A
D
E
L
I
D
V
Nematode Worm
Caenorhab. elegans
P34280
366
40804
T224
V
I
F
R
E
D
C
T
V
D
E
F
I
D
V
Sea Urchin
Strong. purpuratus
XP_790752
363
41012
T223
V
L
F
R
E
D
C
T
P
D
E
F
I
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53295
368
40987
I228
V
R
D
D
Q
C
T
I
D
D
F
I
D
V
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
92
99.7
N.A.
98.6
98
N.A.
73
96.9
56.6
91.4
N.A.
58.4
84
75.1
74.7
Protein Similarity:
100
92.5
92.3
100
N.A.
100
99.7
N.A.
77.1
99.1
71.6
96.4
N.A.
72
90.3
86
85.7
P-Site Identity:
100
6.6
6.6
100
N.A.
93.3
93.3
N.A.
0
100
40
93.3
N.A.
40
86.6
80
93.3
P-Site Similarity:
100
20
20
100
N.A.
100
100
N.A.
20
100
60
100
N.A.
60
86.6
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
77.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
14
0
14
0
0
0
0
0
0
% A
% Cys:
0
7
0
0
0
7
60
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
7
7
74
0
0
14
80
34
0
7
74
0
% D
% Glu:
14
0
0
0
60
7
0
0
0
14
40
0
0
0
0
% E
% Phe:
0
0
60
0
0
0
7
0
0
0
7
54
0
14
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% H
% Ile:
14
7
0
0
0
0
14
14
0
0
7
7
87
0
7
% I
% Lys:
0
14
0
0
0
0
0
0
0
0
0
14
0
0
0
% K
% Leu:
0
54
27
0
0
14
0
14
0
0
0
20
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
14
% N
% Pro:
0
0
0
7
0
0
0
0
47
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
74
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
7
0
7
0
0
47
7
0
0
0
0
0
0
% S
% Thr:
0
14
0
0
0
0
7
27
0
0
0
0
0
0
0
% T
% Val:
67
0
0
14
0
0
0
0
7
7
0
7
0
7
74
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
14
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _