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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRG2
All Species:
48.18
Human Site:
S252
Identified Species:
75.71
UniProt:
P55039
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55039
NP_001379.1
364
40746
S252
Y
N
K
I
D
Q
I
S
M
E
E
V
D
R
L
Chimpanzee
Pan troglodytes
XP_001158439
343
38111
N235
F
I
D
V
I
V
G
N
R
V
Y
M
P
C
L
Rhesus Macaque
Macaca mulatta
XP_001093452
343
38083
N235
F
I
D
V
I
V
G
N
R
V
Y
M
P
C
L
Dog
Lupus familis
XP_536661
364
40714
S252
Y
N
K
I
D
Q
I
S
M
E
E
V
D
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXB9
364
40700
S252
Y
N
K
I
D
Q
I
S
M
E
E
V
D
R
L
Rat
Rattus norvegicus
XP_001076012
364
40701
S252
Y
N
K
I
D
Q
I
S
M
E
E
V
D
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512784
296
33355
D189
Q
I
S
M
E
E
V
D
R
L
A
R
R
P
N
Chicken
Gallus gallus
NP_001025805
364
40687
S252
Y
N
K
I
D
Q
I
S
M
E
E
V
D
R
L
Frog
Xenopus laevis
P43690
367
40396
S254
L
N
K
I
D
Q
I
S
I
E
E
L
D
I
I
Zebra Danio
Brachydanio rerio
NP_997803
364
40863
S252
Y
N
K
V
D
Q
I
S
I
E
E
V
D
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32234
368
41113
S254
L
N
K
I
D
Q
I
S
I
E
E
L
D
V
I
Honey Bee
Apis mellifera
XP_624466
363
40827
S251
H
N
K
I
D
Q
I
S
I
E
E
V
D
R
I
Nematode Worm
Caenorhab. elegans
P34280
366
40804
S252
Y
N
K
V
D
Q
I
S
I
E
E
I
D
R
L
Sea Urchin
Strong. purpuratus
XP_790752
363
41012
S251
Y
N
K
I
D
Q
T
S
I
E
E
V
D
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53295
368
40987
S256
Y
N
K
I
D
A
V
S
L
E
E
V
D
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
92
99.7
N.A.
98.6
98
N.A.
73
96.9
56.6
91.4
N.A.
58.4
84
75.1
74.7
Protein Similarity:
100
92.5
92.3
100
N.A.
100
99.7
N.A.
77.1
99.1
71.6
96.4
N.A.
72
90.3
86
85.7
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
0
100
66.6
86.6
N.A.
66.6
80
80
80
P-Site Similarity:
100
33.3
33.3
100
N.A.
100
100
N.A.
26.6
100
86.6
100
N.A.
86.6
100
100
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
77.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% C
% Asp:
0
0
14
0
80
0
0
7
0
0
0
0
80
0
0
% D
% Glu:
0
0
0
0
7
7
0
0
0
80
80
0
0
0
0
% E
% Phe:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
0
67
14
0
67
0
40
0
0
7
0
7
27
% I
% Lys:
0
0
80
0
0
0
0
0
0
0
0
0
0
7
0
% K
% Leu:
14
0
0
0
0
0
0
0
7
7
0
14
0
0
67
% L
% Met:
0
0
0
7
0
0
0
0
34
0
0
14
0
0
0
% M
% Asn:
0
80
0
0
0
0
0
14
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
14
7
0
% P
% Gln:
7
0
0
0
0
74
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
20
0
0
7
7
60
0
% R
% Ser:
0
0
7
0
0
0
0
80
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
27
0
14
14
0
0
14
0
60
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
60
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _