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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRG2
All Species:
43.33
Human Site:
S269
Identified Species:
68.1
UniProt:
P55039
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55039
NP_001379.1
364
40746
S269
K
P
N
S
V
V
I
S
C
G
M
K
L
N
L
Chimpanzee
Pan troglodytes
XP_001158439
343
38111
S252
Y
N
K
I
D
Q
I
S
M
E
E
V
D
R
L
Rhesus Macaque
Macaca mulatta
XP_001093452
343
38083
S252
Y
N
K
I
D
Q
I
S
M
E
E
V
D
R
L
Dog
Lupus familis
XP_536661
364
40714
S269
K
P
N
S
V
V
I
S
C
G
M
K
L
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXB9
364
40700
S269
K
P
N
S
V
V
I
S
C
G
M
K
L
N
L
Rat
Rattus norvegicus
XP_001076012
364
40701
S269
K
P
N
S
V
V
I
S
C
G
M
K
L
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512784
296
33355
L206
V
I
S
C
G
M
K
L
N
L
D
F
L
L
E
Chicken
Gallus gallus
NP_001025805
364
40687
S269
R
P
H
S
V
V
I
S
C
G
M
K
L
N
L
Frog
Xenopus laevis
P43690
367
40396
S271
V
P
H
C
V
P
I
S
A
H
H
R
W
N
F
Zebra Danio
Brachydanio rerio
NP_997803
364
40863
S269
R
P
N
S
V
V
I
S
C
G
M
K
L
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32234
368
41113
S271
I
P
H
C
V
P
I
S
A
H
H
H
W
N
F
Honey Bee
Apis mellifera
XP_624466
363
40827
S268
Q
P
N
S
V
V
V
S
C
N
M
K
L
N
L
Nematode Worm
Caenorhab. elegans
P34280
366
40804
S269
M
P
H
H
V
V
I
S
C
E
M
N
L
N
M
Sea Urchin
Strong. purpuratus
XP_790752
363
41012
S268
M
P
H
C
L
V
I
S
C
E
M
K
L
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53295
368
40987
S273
E
P
N
T
V
V
M
S
C
E
M
D
L
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
92
99.7
N.A.
98.6
98
N.A.
73
96.9
56.6
91.4
N.A.
58.4
84
75.1
74.7
Protein Similarity:
100
92.5
92.3
100
N.A.
100
99.7
N.A.
77.1
99.1
71.6
96.4
N.A.
72
90.3
86
85.7
P-Site Identity:
100
20
20
100
N.A.
100
100
N.A.
6.6
86.6
33.3
93.3
N.A.
33.3
80
60
66.6
P-Site Similarity:
100
20
20
100
N.A.
100
100
N.A.
20
100
46.6
100
N.A.
40
93.3
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
77.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% A
% Cys:
0
0
0
27
0
0
0
0
67
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
14
0
0
0
0
0
7
7
14
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
34
14
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
14
% F
% Gly:
0
0
0
0
7
0
0
0
0
40
0
0
0
7
0
% G
% His:
0
0
34
7
0
0
0
0
0
14
14
7
0
0
0
% H
% Ile:
7
7
0
14
0
0
80
0
0
0
0
0
0
0
0
% I
% Lys:
27
0
14
0
0
0
7
0
0
0
0
54
0
0
0
% K
% Leu:
0
0
0
0
7
0
0
7
0
7
0
0
74
7
74
% L
% Met:
14
0
0
0
0
7
7
0
14
0
67
0
0
0
7
% M
% Asn:
0
14
47
0
0
0
0
0
7
7
0
7
0
74
0
% N
% Pro:
0
80
0
0
0
14
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% Q
% Arg:
14
0
0
0
0
0
0
0
0
0
0
7
0
14
0
% R
% Ser:
0
0
7
47
0
0
0
94
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
14
0
0
0
74
67
7
0
0
0
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% W
% Tyr:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _