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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRG2
All Species:
37.88
Human Site:
S45
Identified Species:
59.52
UniProt:
P55039
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55039
NP_001379.1
364
40746
S45
R
A
Q
L
L
E
P
S
K
S
A
S
S
K
G
Chimpanzee
Pan troglodytes
XP_001158439
343
38111
S45
R
A
Q
L
L
E
P
S
K
S
A
S
S
K
G
Rhesus Macaque
Macaca mulatta
XP_001093452
343
38083
S45
R
A
Q
L
L
E
P
S
K
S
A
S
S
K
G
Dog
Lupus familis
XP_536661
364
40714
S45
R
A
Q
L
L
E
P
S
K
S
A
S
S
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXB9
364
40700
S45
R
A
Q
L
L
E
P
S
K
S
A
S
S
K
G
Rat
Rattus norvegicus
XP_001076012
364
40701
S45
R
A
Q
L
L
E
P
S
K
S
A
S
S
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512784
296
33355
Chicken
Gallus gallus
NP_001025805
364
40687
S45
R
A
Q
L
L
E
P
S
K
S
S
A
A
K
G
Frog
Xenopus laevis
P43690
367
40396
G47
R
E
L
I
T
P
K
G
G
G
G
G
G
P
G
Zebra Danio
Brachydanio rerio
NP_997803
364
40863
S45
R
A
Q
L
L
E
P
S
K
S
A
G
A
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32234
368
41113
G47
R
E
L
I
S
P
K
G
G
G
G
G
T
G
E
Honey Bee
Apis mellifera
XP_624466
363
40827
P45
R
S
Q
L
L
E
P
P
K
K
S
E
K
G
E
Nematode Worm
Caenorhab. elegans
P34280
366
40804
T45
R
Q
Q
L
L
E
P
T
G
K
G
G
A
K
G
Sea Urchin
Strong. purpuratus
XP_790752
363
41012
T45
R
T
Q
L
L
E
P
T
G
K
S
G
A
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53295
368
40987
A46
Q
Q
L
L
A
D
E
A
G
S
G
G
G
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
92
99.7
N.A.
98.6
98
N.A.
73
96.9
56.6
91.4
N.A.
58.4
84
75.1
74.7
Protein Similarity:
100
92.5
92.3
100
N.A.
100
99.7
N.A.
77.1
99.1
71.6
96.4
N.A.
72
90.3
86
85.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
80
13.3
86.6
N.A.
6.6
46.6
53.3
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
20
93.3
N.A.
20
60
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
77.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
0
7
0
0
7
0
0
47
7
27
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
14
0
0
0
74
7
0
0
0
0
7
0
0
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
14
34
14
27
40
14
20
80
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
14
0
60
20
0
0
7
67
0
% K
% Leu:
0
0
20
80
74
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
14
74
7
0
0
0
0
0
7
0
% P
% Gln:
7
14
74
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
87
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
7
0
0
54
0
60
20
40
40
0
0
% S
% Thr:
0
7
0
0
7
0
0
14
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _