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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DRG2 All Species: 31.52
Human Site: T192 Identified Species: 49.52
UniProt: P55039 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55039 NP_001379.1 364 40746 T192 G G I S F N S T V T L T Q C S
Chimpanzee Pan troglodytes XP_001158439 343 38111 P175 I R L N K H K P N I Y F K P K
Rhesus Macaque Macaca mulatta XP_001093452 343 38083 P175 I R L N K H K P N I Y F K P K
Dog Lupus familis XP_536661 364 40714 T192 G G I S F N S T V T L T Q C S
Cat Felis silvestris
Mouse Mus musculus Q9QXB9 364 40700 T192 G G I S F N S T V T L T Q C S
Rat Rattus norvegicus XP_001076012 364 40701 T192 G G I S F N S T V T L T Q C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512784 296 33355 Q129 N S T V T L T Q C S E K L V Q
Chicken Gallus gallus NP_001025805 364 40687 T192 G G I S F N S T V T L T Q C S
Frog Xenopus laevis P43690 367 40396 T194 G G I N L T A T C A Q S E L D
Zebra Danio Brachydanio rerio NP_997803 364 40863 T192 G G L S Y N S T V P L T Q C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P32234 368 41113 M194 G G I N L N S M V P Q S E L D
Honey Bee Apis mellifera XP_624466 363 40827 T191 G G L A F N S T C P L T K V D
Nematode Worm Caenorhab. elegans P34280 366 40804 T192 G G V K F T N T V P L T H C N
Sea Urchin Strong. purpuratus XP_790752 363 41012 L191 S Q Q L L I T L N Y Y M I K C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53295 368 40987 P196 K V T F T S P P K T N L T E Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 92 99.7 N.A. 98.6 98 N.A. 73 96.9 56.6 91.4 N.A. 58.4 84 75.1 74.7
Protein Similarity: 100 92.5 92.3 100 N.A. 100 99.7 N.A. 77.1 99.1 71.6 96.4 N.A. 72 90.3 86 85.7
P-Site Identity: 100 0 0 100 N.A. 100 100 N.A. 0 100 26.6 80 N.A. 40 53.3 53.3 0
P-Site Similarity: 100 26.6 26.6 100 N.A. 100 100 N.A. 13.3 100 53.3 93.3 N.A. 60 73.3 73.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 58.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 77.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 7 0 0 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 20 0 0 0 0 47 7 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 7 0 14 7 0 % E
% Phe: 0 0 0 7 47 0 0 0 0 0 0 14 0 0 0 % F
% Gly: 67 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 14 0 0 0 0 0 0 7 0 0 % H
% Ile: 14 0 47 0 0 7 0 0 0 14 0 0 7 0 0 % I
% Lys: 7 0 0 7 14 0 14 0 7 0 0 7 20 7 14 % K
% Leu: 0 0 27 7 20 7 0 7 0 0 54 7 7 14 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % M
% Asn: 7 0 0 27 0 54 7 0 20 0 7 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 7 20 0 27 0 0 0 14 0 % P
% Gln: 0 7 7 0 0 0 0 7 0 0 14 0 40 0 14 % Q
% Arg: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 7 7 0 40 0 7 54 0 0 7 0 14 0 0 40 % S
% Thr: 0 0 14 0 14 14 14 60 0 40 0 54 7 0 0 % T
% Val: 0 7 7 7 0 0 0 0 54 0 0 0 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 7 20 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _