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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRG2
All Species:
32.12
Human Site:
Y178
Identified Species:
50.48
UniProt:
P55039
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55039
NP_001379.1
364
40746
Y178
N
K
H
K
P
N
I
Y
F
K
P
K
K
G
G
Chimpanzee
Pan troglodytes
XP_001158439
343
38111
K161
V
Q
R
S
L
L
E
K
E
L
E
S
V
G
I
Rhesus Macaque
Macaca mulatta
XP_001093452
343
38083
K161
V
Q
R
S
L
L
E
K
E
L
E
S
V
G
I
Dog
Lupus familis
XP_536661
364
40714
Y178
N
K
H
K
P
N
I
Y
F
K
P
K
K
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXB9
364
40700
Y178
N
K
H
K
P
N
I
Y
F
K
P
K
K
G
G
Rat
Rattus norvegicus
XP_001076012
364
40701
Y178
N
K
H
K
P
N
I
Y
F
K
P
K
K
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512784
296
33355
K115
N
I
Y
F
K
P
K
K
G
G
G
I
S
F
N
Chicken
Gallus gallus
NP_001025805
364
40687
Y178
N
K
S
K
P
N
I
Y
F
K
P
K
K
G
G
Frog
Xenopus laevis
P43690
367
40396
G180
N
K
Q
P
P
N
I
G
F
K
K
K
D
K
G
Zebra Danio
Brachydanio rerio
NP_997803
364
40863
Y178
N
R
P
K
P
N
I
Y
F
K
P
K
K
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32234
368
41113
Y180
N
K
K
P
P
N
I
Y
Y
K
R
K
D
K
G
Honey Bee
Apis mellifera
XP_624466
363
40827
Y177
N
K
K
K
P
N
I
Y
F
K
I
K
K
G
G
Nematode Worm
Caenorhab. elegans
P34280
366
40804
Y178
N
K
K
P
P
N
I
Y
V
K
Q
K
K
V
G
Sea Urchin
Strong. purpuratus
XP_790752
363
41012
I177
L
N
K
P
R
P
N
I
Y
Y
K
P
Q
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53295
368
40987
K182
K
P
N
I
Y
Y
K
K
K
E
T
G
G
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
92
99.7
N.A.
98.6
98
N.A.
73
96.9
56.6
91.4
N.A.
58.4
84
75.1
74.7
Protein Similarity:
100
92.5
92.3
100
N.A.
100
99.7
N.A.
77.1
99.1
71.6
96.4
N.A.
72
90.3
86
85.7
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
6.6
93.3
60
86.6
N.A.
60
86.6
66.6
0
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
100
N.A.
13.3
93.3
60
93.3
N.A.
66.6
86.6
66.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
77.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% D
% Glu:
0
0
0
0
0
0
14
0
14
7
14
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
54
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
0
7
7
7
7
7
7
60
67
% G
% His:
0
0
27
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
0
67
7
0
0
7
7
0
0
14
% I
% Lys:
7
60
27
47
7
0
14
27
7
67
14
67
54
14
7
% K
% Leu:
7
0
0
0
14
14
0
0
0
14
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
74
7
7
0
0
67
7
0
0
0
0
0
0
0
7
% N
% Pro:
0
7
7
27
67
14
0
0
0
0
40
7
0
0
0
% P
% Gln:
0
14
7
0
0
0
0
0
0
0
7
0
7
0
0
% Q
% Arg:
0
7
14
0
7
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
7
14
0
0
0
0
0
0
0
14
7
7
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% T
% Val:
14
0
0
0
0
0
0
0
7
0
0
0
14
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
7
0
60
14
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _