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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSE1L All Species: 53.94
Human Site: S377 Identified Species: 84.76
UniProt: P55060 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55060 NP_001307.2 971 110417 S377 I R R D L E G S D I D T R R R
Chimpanzee Pan troglodytes XP_001165974 962 109392 S377 I R R D L E G S D I D T R R R
Rhesus Macaque Macaca mulatta XP_001100553 945 107699 S377 I R R D L E G S D I D T R R R
Dog Lupus familis XP_853206 872 98961 A330 V N W K H K D A A I Y L V T S
Cat Felis silvestris
Mouse Mus musculus Q9ERK4 971 110436 S377 I R R D L E G S D I D T R R R
Rat Rattus norvegicus NP_001102077 971 110196 S377 I R R D L E G S D I D T R R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506734 971 110541 S377 I R R D L E G S D I D T R R R
Chicken Gallus gallus XP_417389 971 110338 S377 I R R D L E G S D I D T R R R
Frog Xenopus laevis Q6GMY9 971 109973 S377 I R R D L E G S D I D T R R R
Zebra Danio Brachydanio rerio Q7SZC2 971 110039 S377 I I R D L E G S D I D T R R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XZU1 975 110150 S380 I R R D I E G S D I D T R R R
Honey Bee Apis mellifera XP_395332 967 110282 S378 I R R D I E G S D V D T R R R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001187594 810 91412 K268 P A V N W K Q K D A A T Y L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPY7 972 108639 S384 I R R D M E G S D V D T R R R
Baker's Yeast Sacchar. cerevisiae P33307 960 109338 S372 I R R D L E G S D T D T R R R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.4 97.1 89.5 N.A. 99 98.3 N.A. 95.7 94.5 88 86.7 N.A. 51.9 58.9 N.A. 52.9
Protein Similarity: 100 97.8 97.2 89.6 N.A. 99.6 99.3 N.A. 98.1 97.5 95.6 93.1 N.A. 70.5 75.4 N.A. 66
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 93.3 86.6 N.A. 13.3
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 100 100 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 39.2 35.7 N.A.
Protein Similarity: N.A. N.A. N.A. 60.8 56.5 N.A.
P-Site Identity: N.A. N.A. N.A. 86.6 93.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 100 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 7 7 7 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 87 0 0 7 0 94 0 87 0 0 0 0 % D
% Glu: 0 0 0 0 0 87 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 87 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 87 7 0 0 14 0 0 0 0 74 0 0 0 0 0 % I
% Lys: 0 0 0 7 0 14 0 7 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 67 0 0 0 0 0 0 7 0 7 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Q
% Arg: 0 80 87 0 0 0 0 0 0 0 0 0 87 87 87 % R
% Ser: 0 0 0 0 0 0 0 87 0 0 0 0 0 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 94 0 7 0 % T
% Val: 7 0 7 0 0 0 0 0 0 14 0 0 7 0 7 % V
% Trp: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _