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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSE1L
All Species:
45.15
Human Site:
Y749
Identified Species:
70.95
UniProt:
P55060
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55060
NP_001307.2
971
110417
Y749
A
N
D
H
Q
G
F
Y
L
L
N
S
I
I
E
Chimpanzee
Pan troglodytes
XP_001165974
962
109392
Y749
A
N
D
H
Q
G
F
Y
L
L
N
S
I
I
E
Rhesus Macaque
Macaca mulatta
XP_001100553
945
107699
Y749
A
N
D
H
Q
G
F
Y
L
L
N
S
I
I
E
Dog
Lupus familis
XP_853206
872
98961
N681
L
L
F
Q
R
L
Q
N
S
K
T
T
K
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERK4
971
110436
Y749
A
N
D
H
Q
G
F
Y
L
L
N
S
I
I
E
Rat
Rattus norvegicus
NP_001102077
971
110196
Y749
A
N
D
H
Q
G
F
Y
L
L
N
S
I
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506734
971
110541
Y749
A
N
D
H
Q
G
F
Y
L
L
N
S
I
V
E
Chicken
Gallus gallus
XP_417389
971
110338
Y749
A
N
D
H
Q
G
F
Y
L
L
N
S
I
I
E
Frog
Xenopus laevis
Q6GMY9
971
109973
Y749
A
N
D
H
Q
G
F
Y
L
L
N
S
I
I
E
Zebra Danio
Brachydanio rerio
Q7SZC2
971
110039
Y749
A
N
D
H
Q
G
F
Y
L
L
N
S
I
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZU1
975
110150
Y752
A
N
D
H
E
G
F
Y
L
L
Q
N
L
L
S
Honey Bee
Apis mellifera
XP_395332
967
110282
L749
A
N
D
H
E
G
F
L
L
L
Q
S
I
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187594
810
91412
S619
L
F
N
R
L
I
S
S
K
T
T
K
F
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZPY7
972
108639
Y751
S
T
D
E
Q
G
F
Y
I
L
N
T
I
I
E
Baker's Yeast
Sacchar. cerevisiae
P33307
960
109338
D741
A
Y
E
V
H
G
F
D
L
L
E
H
I
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
97.1
89.5
N.A.
99
98.3
N.A.
95.7
94.5
88
86.7
N.A.
51.9
58.9
N.A.
52.9
Protein Similarity:
100
97.8
97.2
89.6
N.A.
99.6
99.3
N.A.
98.1
97.5
95.6
93.1
N.A.
70.5
75.4
N.A.
66
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
93.3
100
100
93.3
N.A.
60
80
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
86.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.2
35.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
56.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
80
0
0
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
7
14
0
0
0
0
0
7
0
0
0
74
% E
% Phe:
0
7
7
0
0
0
87
0
0
0
0
0
7
7
0
% F
% Gly:
0
0
0
0
0
87
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
74
7
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
7
0
0
0
80
60
7
% I
% Lys:
0
0
0
0
0
0
0
0
7
7
0
7
7
0
7
% K
% Leu:
14
7
0
0
7
7
0
7
80
87
0
0
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
74
7
0
0
0
0
7
0
0
67
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
67
0
7
0
0
0
14
0
0
0
0
% Q
% Arg:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
0
7
7
7
0
0
67
0
0
7
% S
% Thr:
0
7
0
0
0
0
0
0
0
7
14
14
0
0
0
% T
% Val:
0
0
0
7
0
0
0
0
0
0
0
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
74
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _