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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMBIM6
All Species:
26.97
Human Site:
T74
Identified Species:
49.44
UniProt:
P55061
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55061
NP_001092046.1
237
26538
T74
L
M
I
W
L
M
A
T
P
H
S
H
E
T
E
Chimpanzee
Pan troglodytes
XP_509049
348
38122
T185
L
M
I
W
L
M
A
T
P
H
S
H
E
T
E
Rhesus Macaque
Macaca mulatta
XP_001110288
237
26500
T74
L
M
I
W
L
M
A
T
P
H
S
H
E
T
E
Dog
Lupus familis
XP_533325
237
26410
T74
L
M
I
W
L
M
A
T
P
H
S
H
E
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2C7
237
26459
T74
L
M
I
W
L
M
A
T
P
H
S
H
E
T
E
Rat
Rattus norvegicus
P55062
237
26445
T74
L
M
I
C
L
M
A
T
P
H
S
H
E
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663718
236
26467
P74
M
A
W
L
A
M
T
P
H
S
P
Q
T
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSH3
245
27556
Y77
L
V
L
G
L
H
F
Y
K
D
D
G
K
N
Y
Honey Bee
Apis mellifera
XP_624661
236
26628
T71
L
L
F
A
L
V
S
T
P
D
N
G
K
N
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788464
190
21529
A43
L
S
I
L
L
G
F
A
F
C
V
G
V
S
T
Poplar Tree
Populus trichocarpa
XP_002326478
247
27255
I82
C
M
A
W
L
L
S
I
S
P
Y
E
E
Q
K
Maize
Zea mays
NP_001140860
252
27399
V85
S
I
A
W
L
F
S
V
P
V
Y
E
E
R
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD45
247
27465
C81
T
M
I
W
L
L
S
C
P
P
Y
E
H
Q
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
97
94
N.A.
93.6
91.5
N.A.
N.A.
N.A.
N.A.
67.9
N.A.
34.6
43.8
N.A.
38.8
Protein Similarity:
100
68
99.5
99.1
N.A.
98.7
97.4
N.A.
N.A.
N.A.
N.A.
86.9
N.A.
56.7
64.9
N.A.
56.5
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
13.3
26.6
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
20
N.A.
33.3
66.6
N.A.
26.6
Percent
Protein Identity:
44.5
41.6
N.A.
44.1
N.A.
N.A.
Protein Similarity:
63.9
59.9
N.A.
66.4
N.A.
N.A.
P-Site Identity:
26.6
26.6
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
46.6
46.6
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
8
8
0
47
8
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
16
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
24
62
8
47
% E
% Phe:
0
0
8
0
0
8
16
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
0
0
0
0
24
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
8
47
0
47
8
0
0
% H
% Ile:
0
8
62
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
16
0
31
% K
% Leu:
70
8
8
16
93
16
0
0
0
0
0
0
0
0
0
% L
% Met:
8
62
0
0
0
54
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
16
0
% N
% Pro:
0
0
0
0
0
0
0
8
70
16
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
16
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
8
0
0
0
0
31
0
8
8
47
0
0
8
0
% S
% Thr:
8
0
0
0
0
0
8
54
0
0
0
0
8
47
8
% T
% Val:
0
8
0
0
0
8
0
8
0
8
8
0
8
0
0
% V
% Trp:
0
0
8
62
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
24
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _