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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMBIM6
All Species:
27.27
Human Site:
Y134
Identified Species:
50
UniProt:
P55061
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55061
NP_001092046.1
237
26538
Y134
C
F
T
L
S
A
L
Y
A
R
R
R
S
Y
L
Chimpanzee
Pan troglodytes
XP_509049
348
38122
Y245
C
F
T
L
S
A
L
Y
A
R
R
R
S
Y
L
Rhesus Macaque
Macaca mulatta
XP_001110288
237
26500
Y134
C
F
T
L
S
A
L
Y
A
R
R
R
S
Y
L
Dog
Lupus familis
XP_533325
237
26410
Y134
C
F
T
L
S
A
L
Y
A
R
R
R
S
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2C7
237
26459
Y134
C
F
S
L
S
A
L
Y
A
R
R
R
S
Y
L
Rat
Rattus norvegicus
P55062
237
26445
Y134
C
F
S
L
S
A
L
Y
A
R
R
R
S
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663718
236
26467
Y133
C
F
T
L
S
A
L
Y
A
Q
R
R
S
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSH3
245
27556
L137
S
L
S
L
S
A
L
L
A
E
Q
G
K
Y
L
Honey Bee
Apis mellifera
XP_624661
236
26628
L131
S
F
S
I
S
S
L
L
A
E
R
G
R
W
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788464
190
21529
G101
L
A
G
P
L
M
S
G
L
S
M
M
F
I
M
Poplar Tree
Populus trichocarpa
XP_002326478
247
27255
A141
F
S
V
A
A
M
L
A
R
R
R
E
Y
L
Y
Maize
Zea mays
NP_001140860
252
27399
A144
F
T
G
A
A
M
V
A
R
R
R
E
Y
L
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD45
247
27465
A140
F
S
A
A
A
M
L
A
R
R
R
E
Y
L
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
97
94
N.A.
93.6
91.5
N.A.
N.A.
N.A.
N.A.
67.9
N.A.
34.6
43.8
N.A.
38.8
Protein Similarity:
100
68
99.5
99.1
N.A.
98.7
97.4
N.A.
N.A.
N.A.
N.A.
86.9
N.A.
56.7
64.9
N.A.
56.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
46.6
40
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
60
66.6
N.A.
6.6
Percent
Protein Identity:
44.5
41.6
N.A.
44.1
N.A.
N.A.
Protein Similarity:
63.9
59.9
N.A.
66.4
N.A.
N.A.
P-Site Identity:
20
13.3
N.A.
20
N.A.
N.A.
P-Site Similarity:
26.6
26.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
24
24
62
0
24
70
0
0
0
0
0
0
% A
% Cys:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
16
0
24
0
0
0
% E
% Phe:
24
62
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
16
0
0
0
0
8
0
0
0
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
8
8
0
62
8
0
85
16
8
0
0
0
0
24
70
% L
% Met:
0
0
0
0
0
31
0
0
0
0
8
8
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
24
70
85
54
8
0
0
% R
% Ser:
16
16
31
0
70
8
8
0
0
8
0
0
54
0
0
% S
% Thr:
0
8
39
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
24
62
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _