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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AQP5
All Species:
26.67
Human Site:
T242
Identified Species:
58.67
UniProt:
P55064
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55064
NP_001642.1
265
28292
T242
R
V
A
I
I
K
G
T
Y
E
P
D
E
D
W
Chimpanzee
Pan troglodytes
XP_001157125
403
41909
T380
R
V
A
I
I
K
G
T
Y
E
P
D
E
D
W
Rhesus Macaque
Macaca mulatta
XP_001110608
265
28240
T242
R
V
D
I
I
K
G
T
Y
E
P
D
E
D
W
Dog
Lupus familis
XP_543677
337
36148
T314
R
M
A
V
I
K
G
T
Y
E
P
E
E
D
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTY4
265
28256
T242
R
V
A
V
V
K
G
T
Y
E
P
E
E
D
W
Rat
Rattus norvegicus
P47864
265
28403
T242
R
V
A
V
V
K
G
T
Y
E
P
E
E
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518393
255
27145
E234
D
V
D
W
E
E
R
E
A
R
R
R
Q
S
V
Chicken
Gallus gallus
P28238
262
27053
E240
R
L
A
V
L
R
G
E
P
P
A
A
A
P
P
Frog
Xenopus laevis
NP_001079331
273
29418
T240
R
L
A
I
L
K
G
T
Y
Q
P
E
E
A
W
Zebra Danio
Brachydanio rerio
NP_001003534
263
28765
N240
R
L
A
V
L
K
G
N
K
P
T
E
P
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Z7
245
25557
G224
I
A
G
G
L
L
A
G
I
I
Y
R
L
I
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.5
95.8
63.7
N.A.
90.5
90.9
N.A.
61.5
51.7
62.2
53.9
N.A.
38.1
N.A.
N.A.
N.A.
Protein Similarity:
100
65.5
96.5
69.4
N.A.
96.5
96.9
N.A.
76.9
67.5
79.8
71.6
N.A.
56.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
80
N.A.
6.6
20
66.6
26.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
20
46.6
93.3
60
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
73
0
0
0
10
0
10
0
10
10
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
19
0
0
0
0
0
0
0
0
28
0
55
0
% D
% Glu:
0
0
0
0
10
10
0
19
0
55
0
46
64
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
10
10
0
0
82
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
37
37
0
0
0
10
10
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
73
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
28
0
0
37
10
0
0
0
0
0
0
10
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
19
64
0
10
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% Q
% Arg:
82
0
0
0
0
10
10
0
0
10
10
19
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
64
0
0
10
0
0
0
0
% T
% Val:
0
55
0
46
19
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
64
% W
% Tyr:
0
0
0
0
0
0
0
0
64
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _