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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VCP
All Species:
22.73
Human Site:
S705
Identified Species:
41.67
UniProt:
P55072
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55072
NP_009057.1
806
89322
S705
A
I
R
E
S
I
E
S
E
I
R
R
E
R
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852626
806
89284
S705
A
I
R
E
S
I
E
S
E
I
R
R
E
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMC0
893
97237
A799
I
Y
V
P
L
P
D
A
A
T
R
R
E
I
L
Rat
Rattus norvegicus
P46462
806
89330
S705
A
I
R
E
S
I
E
S
E
I
R
R
E
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520419
805
89553
S704
A
I
R
E
S
I
E
S
E
I
R
R
E
R
E
Chicken
Gallus gallus
NP_001038129
806
89306
S705
A
I
R
E
S
I
E
S
E
I
R
R
E
R
E
Frog
Xenopus laevis
P23787
805
89193
N705
A
I
R
E
S
I
E
N
E
I
R
R
E
R
D
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
N705
A
I
R
E
S
I
E
N
E
I
R
R
E
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
A702
A
I
R
Q
A
I
E
A
E
I
R
R
E
K
E
Honey Bee
Apis mellifera
XP_392892
800
88877
T702
A
I
R
Q
S
I
E
T
E
I
R
R
E
K
E
Nematode Worm
Caenorhab. elegans
P54812
810
89622
R710
A
I
R
E
S
I
E
R
E
I
R
Q
E
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZF6
810
89940
K708
A
I
R
E
N
I
E
K
D
I
E
N
E
R
R
Baker's Yeast
Sacchar. cerevisiae
P25694
835
91977
A715
A
I
K
D
S
I
E
A
H
R
Q
H
E
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.8
N.A.
38.5
99.8
N.A.
97.8
99
96.6
96.7
N.A.
83.1
83.6
78.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.8
N.A.
57.1
100
N.A.
98.3
99.7
98.8
98.7
N.A.
92
93
89.2
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
20
100
N.A.
100
100
86.6
93.3
N.A.
73.3
80
80
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
33.3
100
N.A.
100
100
100
100
N.A.
100
100
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
77.1
67.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
87.6
83.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
93
0
0
0
8
0
0
24
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
8
0
0
0
0
0
8
% D
% Glu:
0
0
0
70
0
0
93
0
77
0
8
0
100
0
77
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% H
% Ile:
8
93
0
0
0
93
0
0
0
85
0
0
0
8
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
0
0
0
0
24
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
16
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
16
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
0
0
85
0
0
0
0
8
0
8
85
77
0
62
8
% R
% Ser:
0
0
0
0
77
0
0
39
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _