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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VCP All Species: 33.94
Human Site: S765 Identified Species: 62.22
UniProt: P55072 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55072 NP_009057.1 806 89322 S765 F A Q T L Q Q S R G F G S F R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852626 806 89284 S765 F A Q T L Q Q S R G F G S F R
Cat Felis silvestris
Mouse Mus musculus Q3UMC0 893 97237 N851 A L L A L E E N I K A D C I M
Rat Rattus norvegicus P46462 806 89330 S765 F A Q T L Q Q S R G F G S F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520419 805 89553 S764 F A Q T L Q Q S R G F G S F R
Chicken Gallus gallus NP_001038129 806 89306 S765 F A Q T L Q Q S R G F G S F R
Frog Xenopus laevis P23787 805 89193 S765 F A Q T L Q Q S R G F G S F R
Zebra Danio Brachydanio rerio Q7ZU99 806 89405 S765 F A Q T L Q Q S R G F G S F R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841 L760 Y E M F A Q T L Q Q S R G F G
Honey Bee Apis mellifera XP_392892 800 88877 Q758 R K Y E M F A Q T L Q Q S R G
Nematode Worm Caenorhab. elegans P54812 810 89622 Q769 R K Y E M F A Q T L Q Q S R G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LZF6 810 89940 S769 F A Q T L Q Q S R G F G S E F
Baker's Yeast Sacchar. cerevisiae P25694 835 91977 S787 Y S Q Q M K A S R G Q F S N F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 99.8 N.A. 38.5 99.8 N.A. 97.8 99 96.6 96.7 N.A. 83.1 83.6 78.7 N.A.
Protein Similarity: 100 N.A. N.A. 99.8 N.A. 57.1 100 N.A. 98.3 99.7 98.8 98.7 N.A. 92 93 89.2 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 6.6 100 N.A. 100 100 100 100 N.A. 13.3 6.6 6.6 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 26.6 100 N.A. 100 100 100 100 N.A. 26.6 13.3 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 77.1 67.5 N.A.
Protein Similarity: N.A. N.A. N.A. 87.6 83.2 N.A.
P-Site Identity: N.A. N.A. N.A. 86.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 62 0 8 8 0 24 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 8 0 16 0 8 8 0 0 0 0 0 0 8 0 % E
% Phe: 62 0 0 8 0 16 0 0 0 0 62 8 0 62 16 % F
% Gly: 0 0 0 0 0 0 0 0 0 70 0 62 8 0 24 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % I
% Lys: 0 16 0 0 0 8 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 8 8 0 70 0 0 8 0 16 0 0 0 0 0 % L
% Met: 0 0 8 0 24 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 70 8 0 70 62 16 8 8 24 16 0 0 0 % Q
% Arg: 16 0 0 0 0 0 0 0 70 0 0 8 0 16 54 % R
% Ser: 0 8 0 0 0 0 0 70 0 0 8 0 85 0 0 % S
% Thr: 0 0 0 62 0 0 8 0 16 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _