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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VCP All Species: 30.61
Human Site: S784 Identified Species: 56.11
UniProt: P55072 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55072 NP_009057.1 806 89322 S784 N Q G G A G P S Q G S G G G T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852626 806 89284 S784 N Q G G A G P S Q G S G G G T
Cat Felis silvestris
Mouse Mus musculus Q3UMC0 893 97237 T870 T Q A L S I V T P R I P E S L
Rat Rattus norvegicus P46462 806 89330 S784 N Q G G A G P S Q G S G G G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520419 805 89553 S783 N Q G G A V P S H G S G G S A
Chicken Gallus gallus NP_001038129 806 89306 S784 N Q G G A G P S Q G T G G G S
Frog Xenopus laevis P23787 805 89193 S784 G Q S G A G P S P G A G G G S
Zebra Danio Brachydanio rerio Q7ZU99 806 89405 S784 N Q G G S G P S Q G S S G G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841 T779 F P G Q T G N T S G S G N N L
Honey Bee Apis mellifera XP_392892 800 88877 T777 F R F P Q S G T S G T Q D T T
Nematode Worm Caenorhab. elegans P54812 810 89622 P788 F K F P G E A P S A G Q P V G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LZF6 810 89940 T788 T A G V G R T T G V A A A D P
Baker's Yeast Sacchar. cerevisiae P25694 835 91977 T806 A P L G T T A T D N A N S N N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 99.8 N.A. 38.5 99.8 N.A. 97.8 99 96.6 96.7 N.A. 83.1 83.6 78.7 N.A.
Protein Similarity: 100 N.A. N.A. 99.8 N.A. 57.1 100 N.A. 98.3 99.7 98.8 98.7 N.A. 92 93 89.2 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 6.6 100 N.A. 73.3 86.6 66.6 80 N.A. 33.3 13.3 0 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 20 100 N.A. 73.3 100 80 86.6 N.A. 40 33.3 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 77.1 67.5 N.A.
Protein Similarity: N.A. N.A. N.A. 87.6 83.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 47 0 16 0 0 8 24 8 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 8 8 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % E
% Phe: 24 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 62 62 16 54 8 0 8 70 8 54 54 47 16 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 47 0 0 0 0 0 8 0 0 8 0 8 8 16 8 % N
% Pro: 0 16 0 16 0 0 54 8 16 0 0 8 8 0 8 % P
% Gln: 0 62 0 8 8 0 0 0 39 0 0 16 0 0 0 % Q
% Arg: 0 8 0 0 0 8 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 8 0 16 8 0 54 24 0 47 8 8 16 16 % S
% Thr: 16 0 0 0 16 8 8 39 0 0 16 0 0 8 31 % T
% Val: 0 0 0 8 0 8 8 0 0 8 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _