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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VCP
All Species:
50.3
Human Site:
T122
Identified Species:
92.22
UniProt:
P55072
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55072
NP_009057.1
806
89322
T122
H
V
L
P
I
D
D
T
V
E
G
I
T
G
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852626
806
89284
T122
H
V
L
P
I
D
D
T
V
E
G
I
T
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMC0
893
97237
T271
G
E
V
L
L
D
V
T
Q
S
P
R
D
G
S
Rat
Rattus norvegicus
P46462
806
89330
T122
H
V
L
P
I
D
D
T
V
E
G
I
T
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520419
805
89553
T121
H
V
L
P
I
D
D
T
V
E
G
I
T
G
N
Chicken
Gallus gallus
NP_001038129
806
89306
T122
H
V
L
P
I
D
D
T
V
E
G
I
T
G
N
Frog
Xenopus laevis
P23787
805
89193
T122
H
V
L
P
I
D
D
T
V
E
G
I
T
G
N
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
T122
H
V
L
P
I
D
D
T
V
E
G
I
T
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
S119
R
I
L
P
I
D
E
S
T
E
G
V
T
G
N
Honey Bee
Apis mellifera
XP_392892
800
88877
T119
H
V
L
P
M
D
D
T
V
T
G
L
T
G
N
Nematode Worm
Caenorhab. elegans
P54812
810
89622
T127
H
V
L
P
I
D
D
T
I
E
G
L
T
G
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZF6
810
89940
T126
H
I
L
P
V
D
D
T
V
E
G
V
T
G
N
Baker's Yeast
Sacchar. cerevisiae
P25694
835
91977
T132
S
V
L
P
I
A
D
T
I
E
G
I
T
G
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.8
N.A.
38.5
99.8
N.A.
97.8
99
96.6
96.7
N.A.
83.1
83.6
78.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.8
N.A.
57.1
100
N.A.
98.3
99.7
98.8
98.7
N.A.
92
93
89.2
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
20
100
N.A.
100
100
100
100
N.A.
60
80
86.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
40
100
N.A.
100
100
100
100
N.A.
86.6
93.3
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
77.1
67.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
87.6
83.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
100
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
93
85
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
0
0
0
8
0
0
85
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
93
0
0
100
0
% G
% His:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
77
0
0
0
16
0
0
62
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
93
8
8
0
0
0
0
0
0
16
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
93
% N
% Pro:
0
0
0
93
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
8
0
8
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
93
8
8
0
0
93
0
0
% T
% Val:
0
77
8
0
8
0
8
0
70
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _