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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VCP All Species: 39.39
Human Site: T76 Identified Species: 72.22
UniProt: P55072 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55072 NP_009057.1 806 89322 T76 C I V L S D D T C S D E K I R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852626 806 89284 T76 C I V L S D D T C S D E K I R
Cat Felis silvestris
Mouse Mus musculus Q3UMC0 893 97237 D229 S M E S S D V D L S F Q L S Q
Rat Rattus norvegicus P46462 806 89330 T76 C I V L S D D T C S D E K I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520419 805 89553 T75 C I V L S D D T C S D E K I R
Chicken Gallus gallus NP_001038129 806 89306 T76 C I V L S D D T C S D E K I R
Frog Xenopus laevis P23787 805 89193 T76 C I V L S D D T C S D E K I R
Zebra Danio Brachydanio rerio Q7ZU99 806 89405 T76 C I V L S D D T C S D E K V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841 T73 C I V L S D D T C P D E K I R
Honey Bee Apis mellifera XP_392892 800 88877 T73 C I V L S D D T C P D E K I R
Nematode Worm Caenorhab. elegans P54812 810 89622 N82 S I V L N A D N C P N D K I K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LZF6 810 89940 T80 C I A L A D E T C E E P K I R
Baker's Yeast Sacchar. cerevisiae P25694 835 91977 E86 L I V L I D D E L E D G A C R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 99.8 N.A. 38.5 99.8 N.A. 97.8 99 96.6 96.7 N.A. 83.1 83.6 78.7 N.A.
Protein Similarity: 100 N.A. N.A. 99.8 N.A. 57.1 100 N.A. 98.3 99.7 98.8 98.7 N.A. 92 93 89.2 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 20 100 N.A. 100 100 100 93.3 N.A. 93.3 93.3 46.6 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 40 100 N.A. 100 100 100 100 N.A. 93.3 93.3 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 77.1 67.5 N.A.
Protein Similarity: N.A. N.A. N.A. 87.6 83.2 N.A.
P-Site Identity: N.A. N.A. N.A. 60 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 8 0 0 0 0 0 0 8 0 0 % A
% Cys: 77 0 0 0 0 0 0 0 85 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 93 85 8 0 0 77 8 0 0 0 % D
% Glu: 0 0 8 0 0 0 8 8 0 16 8 70 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 93 0 0 8 0 0 0 0 0 0 0 0 77 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 85 0 8 % K
% Leu: 8 0 0 93 0 0 0 0 16 0 0 0 8 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 8 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 24 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85 % R
% Ser: 16 0 0 8 77 0 0 0 0 62 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 % T
% Val: 0 0 85 0 0 0 8 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _