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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VCP
All Species:
50.3
Human Site:
Y495
Identified Species:
92.22
UniProt:
P55072
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55072
NP_009057.1
806
89322
Y495
E
L
Q
E
L
V
Q
Y
P
V
E
H
P
D
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852626
806
89284
Y495
E
L
Q
E
L
V
Q
Y
P
V
E
H
P
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMC0
893
97237
S612
G
M
N
D
I
R
P
S
A
M
R
E
V
A
I
Rat
Rattus norvegicus
P46462
806
89330
Y495
E
L
Q
E
L
V
Q
Y
P
V
E
H
P
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520419
805
89553
Y494
E
L
Q
E
L
V
Q
Y
P
V
E
H
P
D
K
Chicken
Gallus gallus
NP_001038129
806
89306
Y495
E
L
Q
E
L
V
Q
Y
P
V
E
H
P
D
K
Frog
Xenopus laevis
P23787
805
89193
Y495
E
L
Q
E
L
V
Q
Y
P
V
E
H
P
D
K
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
Y495
E
L
Q
E
L
V
Q
Y
P
V
E
H
P
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
Y492
E
L
Q
E
L
V
Q
Y
P
V
E
H
P
D
K
Honey Bee
Apis mellifera
XP_392892
800
88877
Y492
E
L
Q
E
L
V
Q
Y
P
V
E
H
P
D
K
Nematode Worm
Caenorhab. elegans
P54812
810
89622
Y500
E
L
Q
E
L
V
Q
Y
P
V
E
H
P
E
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZF6
810
89940
Y498
E
L
Q
E
T
V
Q
Y
P
V
E
H
P
E
K
Baker's Yeast
Sacchar. cerevisiae
P25694
835
91977
Y505
E
L
K
E
T
V
E
Y
P
V
L
H
P
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.8
N.A.
38.5
99.8
N.A.
97.8
99
96.6
96.7
N.A.
83.1
83.6
78.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.8
N.A.
57.1
100
N.A.
98.3
99.7
98.8
98.7
N.A.
92
93
89.2
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
0
100
N.A.
100
100
100
100
N.A.
100
100
93.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
26.6
100
N.A.
100
100
100
100
N.A.
100
100
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
77.1
67.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
87.6
83.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
86.6
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
77
0
% D
% Glu:
93
0
0
93
0
0
8
0
0
0
85
8
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
85
% K
% Leu:
0
93
0
0
77
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
93
0
0
0
93
0
0
% P
% Gln:
0
0
85
0
0
0
85
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
93
0
0
0
93
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _