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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VCP
All Species:
34.85
Human Site:
Y755
Identified Species:
63.89
UniProt:
P55072
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55072
NP_009057.1
806
89322
Y755
S
D
N
D
I
R
K
Y
E
M
F
A
Q
T
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852626
806
89284
Y755
S
D
N
D
I
R
K
Y
E
M
F
A
Q
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMC0
893
97237
K841
A
E
I
I
A
V
C
K
E
A
A
L
L
A
L
Rat
Rattus norvegicus
P46462
806
89330
Y755
S
D
N
D
I
R
K
Y
E
M
F
A
Q
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520419
805
89553
Y754
S
D
N
D
I
R
K
Y
E
M
F
A
Q
T
L
Chicken
Gallus gallus
NP_001038129
806
89306
Y755
S
D
N
D
I
R
K
Y
E
M
F
A
Q
T
L
Frog
Xenopus laevis
P23787
805
89193
Y755
S
D
N
D
I
R
K
Y
E
M
F
A
Q
T
L
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
Y755
S
D
N
D
I
R
K
Y
E
M
F
A
Q
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
I750
R
S
V
S
D
N
D
I
R
K
Y
E
M
F
A
Honey Bee
Apis mellifera
XP_392892
800
88877
N748
A
R
R
S
V
S
D
N
D
I
R
K
Y
E
M
Nematode Worm
Caenorhab. elegans
P54812
810
89622
N759
A
R
R
S
V
T
D
N
D
I
R
K
Y
E
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZF6
810
89940
Y759
S
D
A
D
I
R
K
Y
Q
A
F
A
Q
T
L
Baker's Yeast
Sacchar. cerevisiae
P25694
835
91977
Y777
S
D
A
E
L
R
R
Y
E
A
Y
S
Q
Q
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.8
N.A.
38.5
99.8
N.A.
97.8
99
96.6
96.7
N.A.
83.1
83.6
78.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.8
N.A.
57.1
100
N.A.
98.3
99.7
98.8
98.7
N.A.
92
93
89.2
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
13.3
100
N.A.
100
100
100
100
N.A.
0
0
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
26.6
100
N.A.
100
100
100
100
N.A.
6.6
33.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
77.1
67.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
87.6
83.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
16
0
8
0
0
0
0
24
8
62
0
8
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
0
62
8
0
24
0
16
0
0
0
0
0
0
% D
% Glu:
0
8
0
8
0
0
0
0
70
0
0
8
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
62
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
62
0
0
8
0
16
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
62
8
0
8
0
16
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
70
% L
% Met:
0
0
0
0
0
0
0
0
0
54
0
0
8
0
24
% M
% Asn:
0
0
54
0
0
8
0
16
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
70
8
0
% Q
% Arg:
8
16
16
0
0
70
8
0
8
0
16
0
0
0
0
% R
% Ser:
70
8
0
24
0
8
0
0
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
62
0
% T
% Val:
0
0
8
0
16
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
16
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _