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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VCP All Species: 18.48
Human Site: Y796 Identified Species: 33.89
UniProt: P55072 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55072 NP_009057.1 806 89322 Y796 G G T G G S V Y T E D N D D D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852626 806 89284 Y796 G G T G G S V Y T E D N D D D
Cat Felis silvestris
Mouse Mus musculus Q3UMC0 893 97237 E882 E S L R R F Y E D Y Q E K S G
Rat Rattus norvegicus P46462 806 89330 Y796 G G T G G N V Y T E D N D D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520419 805 89553 Y795 G S A G G N V Y R G D K E N D
Chicken Gallus gallus NP_001038129 806 89306 Y796 G G S G G N V Y S E D N D D D
Frog Xenopus laevis P23787 805 89193 F796 G G S G G G H F T E E D D D L
Zebra Danio Brachydanio rerio Q7ZU99 806 89405 F796 G G G G G N V F N E D N D D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841 P791 N N L P V N S P G D N G D D D
Honey Bee Apis mellifera XP_392892 800 88877 A789 D T T Q G D Q A F Q D D G D D
Nematode Worm Caenorhab. elegans P54812 810 89622 S800 P V G G N G G S G G N D D D D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LZF6 810 89940 A800 A D P F A T S A A A A D D D D
Baker's Yeast Sacchar. cerevisiae P25694 835 91977 G818 S N N S A P S G A G A A F G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 99.8 N.A. 38.5 99.8 N.A. 97.8 99 96.6 96.7 N.A. 83.1 83.6 78.7 N.A.
Protein Similarity: 100 N.A. N.A. 99.8 N.A. 57.1 100 N.A. 98.3 99.7 98.8 98.7 N.A. 92 93 89.2 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 0 93.3 N.A. 46.6 80 53.3 73.3 N.A. 20 33.3 26.6 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 0 100 N.A. 66.6 100 80 86.6 N.A. 40 46.6 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 77.1 67.5 N.A.
Protein Similarity: N.A. N.A. N.A. 87.6 83.2 N.A.
P-Site Identity: N.A. N.A. N.A. 20 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 16 0 0 16 16 8 16 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 8 0 0 8 8 54 31 70 77 77 % D
% Glu: 8 0 0 0 0 0 0 8 0 47 8 8 8 0 0 % E
% Phe: 0 0 0 8 0 8 0 16 8 0 0 0 8 0 0 % F
% Gly: 54 47 16 62 62 16 8 8 16 24 0 8 8 8 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % K
% Leu: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 16 8 0 8 39 0 0 8 0 16 39 0 8 0 % N
% Pro: 8 0 8 8 0 8 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 8 0 0 8 8 0 0 0 0 % Q
% Arg: 0 0 0 8 8 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 8 16 16 8 0 16 24 8 8 0 0 0 0 8 8 % S
% Thr: 0 8 31 0 0 8 0 0 31 0 0 0 0 0 0 % T
% Val: 0 8 0 0 8 0 47 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 39 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _