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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGF8
All Species:
16.97
Human Site:
S138
Identified Species:
41.48
UniProt:
P55075
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55075
NP_006110.1
233
26525
S138
K
G
K
L
I
A
K
S
N
G
K
G
K
D
C
Chimpanzee
Pan troglodytes
XP_001170220
233
26619
S138
Y
L
V
T
G
L
R
S
P
G
K
G
K
D
C
Rhesus Macaque
Macaca mulatta
XP_001103818
160
18290
K70
A
K
S
N
G
K
G
K
D
C
V
F
T
E
I
Dog
Lupus familis
XP_851783
287
32042
S192
K
G
K
L
I
A
K
S
N
G
K
G
K
D
C
Cat
Felis silvestris
Mouse
Mus musculus
P37237
268
30401
S173
K
G
K
L
I
A
K
S
N
G
K
G
K
D
C
Rat
Rattus norvegicus
P63076
216
24906
P120
R
G
K
L
I
G
K
P
S
G
K
S
K
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518165
242
27776
P146
R
G
K
L
V
G
K
P
S
G
K
S
K
D
C
Chicken
Gallus gallus
Q90722
214
24788
S120
K
G
K
L
I
G
K
S
N
G
K
G
K
D
C
Frog
Xenopus laevis
Q91875
209
23644
Y116
R
G
V
D
S
G
L
Y
L
G
M
N
E
K
G
Zebra Danio
Brachydanio rerio
Q805B2
212
24957
R122
K
G
K
L
I
G
R
R
K
G
R
G
K
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.1
64.3
72.8
N.A.
81.3
55.7
N.A.
48.7
70.8
21.4
58.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.9
66.5
74.5
N.A.
83.5
69.5
N.A.
65.6
77.2
39.4
68.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
0
100
N.A.
100
66.6
N.A.
60
93.3
13.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
13.3
100
N.A.
100
80
N.A.
80
93.3
26.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
80
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
0
80
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
80
0
0
20
50
10
0
0
90
0
60
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
50
10
70
0
0
10
60
10
10
0
70
0
80
10
0
% K
% Leu:
0
10
0
70
0
10
10
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
40
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
20
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
30
0
0
0
0
0
20
10
0
0
10
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
0
50
20
0
0
20
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
20
0
10
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _