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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HADHB All Species: 31.82
Human Site: S113 Identified Species: 58.33
UniProt: P55084 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55084 NP_000174.1 474 51294 S113 V I Q E V K T S N V A R E A A
Chimpanzee Pan troglodytes Q5R1W7 475 51377 S114 V I Q E V K T S N V A R E A A
Rhesus Macaque Macaca mulatta XP_001086547 482 52253 S114 V I Q E V K T S N V A R E A A
Dog Lupus familis XP_849696 475 51211 S114 V I Q E V K T S N V A R E A A
Cat Felis silvestris
Mouse Mus musculus Q99JY0 475 51368 S114 V I Q E V K T S N V A R E A A
Rat Rattus norvegicus Q60587 475 51396 S114 V I Q E V K T S N V A R E A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509364 555 59898 S194 V I Q E V K T S N V A R E A A
Chicken Gallus gallus XP_420004 474 50831 S113 V I Q E V K T S N V A R E A A
Frog Xenopus laevis NP_001080077 470 50522 E114 K T S N V A R E A A L G A G F
Zebra Danio Brachydanio rerio NP_956313 471 49953 N111 I Q E V K T S N V A R E A A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477378 469 50623 A112 I A R E A A L A A G F S N K T
Honey Bee Apis mellifera XP_624164 466 50900 G112 R E A A L T A G Y S D R I P A
Nematode Worm Caenorhab. elegans P34255 448 47856 P98 A A L L A G V P D K I P A H T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 95.2 94.3 N.A. 90.9 89.6 N.A. 75.8 83.9 82.9 78.4 N.A. 65.6 62.6 59 N.A.
Protein Similarity: 100 99.7 96.6 98.1 N.A. 96.8 97 N.A. 82.5 93.6 92.1 89.2 N.A. 79.7 78 74.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 6.6 6.6 N.A. 6.6 13.3 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 6.6 33.3 N.A. 26.6 20 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 8 8 16 16 8 8 16 16 62 0 24 70 70 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % D
% Glu: 0 8 8 70 0 0 0 8 0 0 0 8 62 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % F
% Gly: 0 0 0 0 0 8 0 8 0 8 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 16 62 0 0 0 0 0 0 0 0 8 0 8 0 0 % I
% Lys: 8 0 0 0 8 62 0 0 0 8 0 0 0 8 0 % K
% Leu: 0 0 8 8 8 0 8 0 0 0 8 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 8 62 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 8 0 8 0 % P
% Gln: 0 8 62 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 8 0 0 0 8 0 0 0 8 70 0 0 0 % R
% Ser: 0 0 8 0 0 0 8 62 0 8 0 8 0 0 0 % S
% Thr: 0 8 0 0 0 16 62 0 0 0 0 0 0 0 16 % T
% Val: 62 0 0 8 70 0 8 0 8 62 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _