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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HADHB All Species: 32.42
Human Site: Y336 Identified Species: 59.44
UniProt: P55084 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55084 NP_000174.1 474 51294 Y336 M G Y K P K A Y L R D F M Y V
Chimpanzee Pan troglodytes Q5R1W7 475 51377 Y337 M G Y K P K A Y L R D F M Y V
Rhesus Macaque Macaca mulatta XP_001086547 482 52253 Y337 M G Y K P K A Y L R D F M Y V
Dog Lupus familis XP_849696 475 51211 Y337 M G Y K P K A Y L R D F V Y V
Cat Felis silvestris
Mouse Mus musculus Q99JY0 475 51368 Y337 M G Y K P K A Y L R D F I Y V
Rat Rattus norvegicus Q60587 475 51396 Y337 M G Y K P K A Y L R D F I Y V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509364 555 59898 Y417 M G Y K P K A Y L R D F V Y V
Chicken Gallus gallus XP_420004 474 50831 Y336 L G Y K P K A Y L R D F V Y V
Frog Xenopus laevis NP_001080077 470 50522 V337 K A Y L R D F V Y V S Q D P K
Zebra Danio Brachydanio rerio NP_956313 471 49953 L334 G Y K P K A Y L R D F V Y V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477378 469 50623 S335 L R D F L F V S Q D P V N Q L
Honey Bee Apis mellifera XP_624164 466 50900 D335 N F I Y V S Q D P I D Q L L L
Nematode Worm Caenorhab. elegans P34255 448 47856 P321 Y L Y V A Q D P K D Q L L L S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 95.2 94.3 N.A. 90.9 89.6 N.A. 75.8 83.9 82.9 78.4 N.A. 65.6 62.6 59 N.A.
Protein Similarity: 100 99.7 96.6 98.1 N.A. 96.8 97 N.A. 82.5 93.6 92.1 89.2 N.A. 79.7 78 74.2 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 86.6 6.6 0 N.A. 0 6.6 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 6.6 0 N.A. 13.3 20 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 8 62 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 8 8 8 0 24 70 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 8 0 8 8 0 0 0 8 62 0 0 0 % F
% Gly: 8 62 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 8 0 0 16 0 0 % I
% Lys: 8 0 8 62 8 62 0 0 8 0 0 0 0 0 8 % K
% Leu: 16 8 0 8 8 0 0 8 62 0 0 8 16 16 16 % L
% Met: 54 0 0 0 0 0 0 0 0 0 0 0 24 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 8 62 0 0 8 8 0 8 0 0 8 0 % P
% Gln: 0 0 0 0 0 8 8 0 8 0 8 16 0 8 0 % Q
% Arg: 0 8 0 0 8 0 0 0 8 62 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 8 0 8 0 0 8 0 0 0 16 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 8 8 0 8 8 0 8 0 16 24 8 62 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 77 8 0 0 8 62 8 0 0 0 8 62 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _