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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF10
All Species:
17.58
Human Site:
S222
Identified Species:
32.22
UniProt:
P55107
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55107
NP_004953.1
478
53122
S222
R
D
G
E
L
L
L
S
A
Q
L
D
S
E
E
Chimpanzee
Pan troglodytes
XP_001135281
477
52965
S221
R
D
G
E
L
L
L
S
A
Q
L
D
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001109475
477
52865
S221
R
D
G
E
L
L
L
S
A
Q
L
D
S
E
E
Dog
Lupus familis
XP_853904
651
71186
W393
Q
A
G
E
L
L
L
W
A
Q
L
D
P
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P97737
476
52472
S218
R
D
G
E
L
L
L
S
A
Q
L
D
T
G
E
Rat
Rattus norvegicus
P55108
476
52942
S218
R
D
G
E
L
L
L
S
A
Q
L
D
S
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507675
405
46274
P189
F
P
A
G
D
P
D
P
S
R
S
P
N
A
S
Chicken
Gallus gallus
Q90751
353
40328
A139
E
I
M
K
P
A
T
A
T
S
K
D
P
V
T
Frog
Xenopus laevis
Q7T2X6
443
50638
M192
E
R
D
L
F
I
S
M
E
I
S
F
G
E
K
Zebra Danio
Brachydanio rerio
P35621
355
40183
D142
G
P
H
V
F
S
V
D
L
Y
R
V
L
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
P239
S
L
F
N
M
K
R
P
P
K
I
D
R
S
K
Honey Bee
Apis mellifera
XP_392320
529
60859
I281
R
G
D
G
N
D
E
I
E
Q
V
F
H
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
L182
V
S
L
K
D
K
R
L
R
L
L
D
V
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
94.7
55.6
N.A.
83.4
83.6
N.A.
57.7
24
47.7
22.7
N.A.
21.6
25.5
N.A.
22.5
Protein Similarity:
100
98.5
96.4
62.9
N.A.
88.9
88.9
N.A.
66.1
39.3
61.9
37
N.A.
37.5
36.2
N.A.
38.7
P-Site Identity:
100
100
100
60
N.A.
86.6
93.3
N.A.
0
6.6
6.6
0
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
100
100
66.6
N.A.
93.3
93.3
N.A.
20
20
20
13.3
N.A.
33.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
0
8
47
0
0
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
39
16
0
16
8
8
8
0
0
0
70
0
8
0
% D
% Glu:
16
0
0
47
0
0
8
0
16
0
0
0
0
31
47
% E
% Phe:
8
0
8
0
16
0
0
0
0
0
0
16
0
0
0
% F
% Gly:
8
8
47
16
0
0
0
0
0
0
0
0
8
16
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
8
0
8
0
8
8
0
0
0
0
% I
% Lys:
0
0
0
16
0
16
0
0
0
8
8
0
0
8
16
% K
% Leu:
0
8
8
8
47
47
47
8
8
8
54
0
8
0
8
% L
% Met:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
16
0
0
8
8
0
16
8
0
0
8
16
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% Q
% Arg:
47
8
0
0
0
0
16
0
8
8
8
0
8
0
0
% R
% Ser:
8
8
0
0
0
8
8
39
8
8
16
0
31
8
8
% S
% Thr:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
16
% T
% Val:
8
0
0
8
0
0
8
0
0
0
8
8
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _