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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GDF10 All Species: 21.52
Human Site: S238 Identified Species: 39.44
UniProt: P55107 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55107 NP_004953.1 478 53122 S238 D P G V P R P S P Y A P Y I L
Chimpanzee Pan troglodytes XP_001135281 477 52965 S237 D P G V P Q P S P Y A P Y I L
Rhesus Macaque Macaca mulatta XP_001109475 477 52865 S237 D P G V P R P S P Y A P Y I L
Dog Lupus familis XP_853904 651 71186 S409 A P G A A G P S A P L P Y L L
Cat Felis silvestris
Mouse Mus musculus P97737 476 52472 S234 D P G V P R P S S H M P Y I L
Rat Rattus norvegicus P55108 476 52942 S234 D L G V P R P S S H M P Y I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507675 405 46274 T205 D T R V R R D T Y V P G S I Q
Chicken Gallus gallus Q90751 353 40328 H155 L L D T R L V H H N A S K W E
Frog Xenopus laevis Q7T2X6 443 50638 P208 A T V F E N N P S E L P Y I L
Zebra Danio Brachydanio rerio P35621 355 40183 S158 L K G V T H E S S R K L L Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07713 588 65849 K255 I I P E P M K K L Y A E I M G
Honey Bee Apis mellifera XP_392320 529 60859 N297 E E K G D W R N S D A E Q D P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P48970 395 43818 G198 D L S Q G Y A G T I D I L S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 94.7 55.6 N.A. 83.4 83.6 N.A. 57.7 24 47.7 22.7 N.A. 21.6 25.5 N.A. 22.5
Protein Similarity: 100 98.5 96.4 62.9 N.A. 88.9 88.9 N.A. 66.1 39.3 61.9 37 N.A. 37.5 36.2 N.A. 38.7
P-Site Identity: 100 93.3 100 46.6 N.A. 80 73.3 N.A. 26.6 6.6 26.6 20 N.A. 20 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 53.3 N.A. 86.6 80 N.A. 33.3 6.6 26.6 20 N.A. 26.6 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 8 8 0 8 0 8 0 47 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 54 0 8 0 8 0 8 0 0 8 8 0 0 8 0 % D
% Glu: 8 8 0 8 8 0 8 0 0 8 0 16 0 0 8 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 54 8 8 8 0 8 0 0 0 8 0 0 8 % G
% His: 0 0 0 0 0 8 0 8 8 16 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 0 8 0 8 8 54 0 % I
% Lys: 0 8 8 0 0 0 8 8 0 0 8 0 8 0 0 % K
% Leu: 16 24 0 0 0 8 0 0 8 0 16 8 16 8 54 % L
% Met: 0 0 0 0 0 8 0 0 0 0 16 0 0 8 0 % M
% Asn: 0 0 0 0 0 8 8 8 0 8 0 0 0 0 0 % N
% Pro: 0 39 8 0 47 0 47 8 24 8 8 54 0 0 8 % P
% Gln: 0 0 0 8 0 8 0 0 0 0 0 0 8 8 8 % Q
% Arg: 0 0 8 0 16 39 8 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 8 0 0 0 0 54 39 0 0 8 8 8 8 % S
% Thr: 0 16 0 8 8 0 0 8 8 0 0 0 0 0 8 % T
% Val: 0 0 8 54 0 0 8 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 8 0 0 8 31 0 0 54 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _