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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GDF10 All Species: 30
Human Site: Y404 Identified Species: 55
UniProt: P55107 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55107 NP_004953.1 478 53122 Y404 P K S F D A Y Y C A G A C E F
Chimpanzee Pan troglodytes XP_001135281 477 52965 Y403 P K S F D A Y Y C A G A C E F
Rhesus Macaque Macaca mulatta XP_001109475 477 52865 Y403 P K S F D A Y Y C A G A C E F
Dog Lupus familis XP_853904 651 71186 Y577 P K S F D A Y Y C A G E C E F
Cat Felis silvestris
Mouse Mus musculus P97737 476 52472 Y402 P K S F D A Y Y C A G A C E F
Rat Rattus norvegicus P55108 476 52942 Y402 P K S F D A Y Y C A G A C E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507675 405 46274 M340 A G A C E F P M P K I V R P S
Chicken Gallus gallus Q90751 353 40328 L290 H G E C P F P L A D H L N S T
Frog Xenopus laevis Q7T2X6 443 50638 Y369 P K S F D A Y Y C S G A C E F
Zebra Danio Brachydanio rerio P35621 355 40183 E293 E C P F P L S E S L N G T N H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07713 588 65849 Y515 P L G Y D A Y Y C H G K C P F
Honey Bee Apis mellifera XP_392320 529 60859 H455 P L G Y S A F H C K G I C E S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P48970 395 43818 E333 E C P F P L G E R L N G T N H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 94.7 55.6 N.A. 83.4 83.6 N.A. 57.7 24 47.7 22.7 N.A. 21.6 25.5 N.A. 22.5
Protein Similarity: 100 98.5 96.4 62.9 N.A. 88.9 88.9 N.A. 66.1 39.3 61.9 37 N.A. 37.5 36.2 N.A. 38.7
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 0 0 93.3 6.6 N.A. 60 40 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 13.3 0 100 6.6 N.A. 66.6 60 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 70 0 0 8 47 0 47 0 0 0 % A
% Cys: 0 16 0 16 0 0 0 0 70 0 0 0 70 0 0 % C
% Asp: 0 0 0 0 62 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 16 0 8 0 8 0 0 16 0 0 0 8 0 62 0 % E
% Phe: 0 0 0 70 0 16 8 0 0 0 0 0 0 0 62 % F
% Gly: 0 16 16 0 0 0 8 0 0 0 70 16 0 0 0 % G
% His: 8 0 0 0 0 0 0 8 0 8 8 0 0 0 16 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % I
% Lys: 0 54 0 0 0 0 0 0 0 16 0 8 0 0 0 % K
% Leu: 0 16 0 0 0 16 0 8 0 16 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 16 0 8 16 0 % N
% Pro: 70 0 16 0 24 0 16 0 8 0 0 0 0 16 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % R
% Ser: 0 0 54 0 8 0 8 0 8 8 0 0 0 8 16 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 16 0 0 62 62 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _