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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GDF10 All Species: 23.64
Human Site: Y86 Identified Species: 43.33
UniProt: P55107 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55107 NP_004953.1 478 53122 Y86 M H R L Y E K Y S R Q G A R P
Chimpanzee Pan troglodytes XP_001135281 477 52965 Y85 M H R L Y E K Y S R Q G A R P
Rhesus Macaque Macaca mulatta XP_001109475 477 52865 Y85 M H R V Y E K Y S R R G A R L
Dog Lupus familis XP_853904 651 71186 Y258 M L R L Y D K Y G R R G A R P
Cat Felis silvestris
Mouse Mus musculus P97737 476 52472 Y82 M L R L Y E K Y N R R G A P P
Rat Rattus norvegicus P55108 476 52942 Y82 M L R L Y E K Y N R R G A P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507675 405 46274 S67 R E A F C K R S K N S S C R L
Chicken Gallus gallus Q90751 353 40328 L18 G E F E L R L L H M F G L K R
Frog Xenopus laevis Q7T2X6 443 50638 N69 G S R L Q D G N T V R S F R A
Zebra Danio Brachydanio rerio P35621 355 40183 D21 S L C S P A E D D G L V Q E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07713 588 65849 P95 R S K T N K K P S K S D A N R
Honey Bee Apis mellifera XP_392320 529 60859 G111 N N V A D P S G V T R G R N P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P48970 395 43818 Y61 P Q Y M W D L Y R Q Q M A A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 94.7 55.6 N.A. 83.4 83.6 N.A. 57.7 24 47.7 22.7 N.A. 21.6 25.5 N.A. 22.5
Protein Similarity: 100 98.5 96.4 62.9 N.A. 88.9 88.9 N.A. 66.1 39.3 61.9 37 N.A. 37.5 36.2 N.A. 38.7
P-Site Identity: 100 100 80 73.3 N.A. 73.3 73.3 N.A. 6.6 6.6 20 0 N.A. 20 13.3 N.A. 20
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 20 13.3 40 6.6 N.A. 40 26.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 0 0 0 0 0 0 62 8 8 % A
% Cys: 0 0 8 0 8 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 8 24 0 8 8 0 0 8 0 0 0 % D
% Glu: 0 16 0 8 0 39 8 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 8 8 0 0 0 0 0 0 8 0 8 0 0 % F
% Gly: 16 0 0 0 0 0 8 8 8 8 0 62 0 0 0 % G
% His: 0 24 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 16 54 0 8 8 0 0 0 8 8 % K
% Leu: 0 31 0 47 8 0 16 8 0 0 8 0 8 0 16 % L
% Met: 47 0 0 8 0 0 0 0 0 8 0 8 0 0 0 % M
% Asn: 8 8 0 0 8 0 0 8 16 8 0 0 0 16 0 % N
% Pro: 8 0 0 0 8 8 0 8 0 0 0 0 0 16 47 % P
% Gln: 0 8 0 0 8 0 0 0 0 8 24 0 8 0 0 % Q
% Arg: 16 0 54 0 0 8 8 0 8 47 47 0 8 47 16 % R
% Ser: 8 16 0 8 0 0 8 8 31 0 16 16 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 0 8 8 0 0 0 0 8 % T
% Val: 0 0 8 8 0 0 0 0 8 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 47 0 0 54 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _