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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANF
All Species:
17.27
Human Site:
S19
Identified Species:
38
UniProt:
P55145
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55145
NP_006001.2
179
20257
S19
A
L
S
V
L
P
G
S
R
A
L
R
P
G
D
Chimpanzee
Pan troglodytes
XP_001169644
246
27914
S86
A
L
S
V
L
P
G
S
R
S
L
R
P
G
D
Rhesus Macaque
Macaca mulatta
XP_001088321
187
20989
A29
V
L
A
Q
G
Q
E
A
G
G
R
P
G
A
D
Dog
Lupus familis
XP_850540
179
20362
G19
A
L
S
V
L
P
G
G
R
T
L
R
P
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXI5
179
20355
S19
A
L
S
V
L
P
D
S
R
A
L
R
P
G
D
Rat
Rattus norvegicus
P0C5H9
179
20369
S19
A
L
S
V
L
P
D
S
R
A
L
R
P
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506741
196
22383
W36
L
S
S
R
C
G
D
W
L
L
K
N
R
P
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666400
180
20155
S20
L
A
L
V
P
S
C
S
D
A
L
K
D
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ63
173
20118
S20
L
A
T
L
A
Q
T
S
L
A
L
K
E
E
D
Honey Bee
Apis mellifera
XP_625023
175
20050
V19
V
I
G
L
I
Y
T
V
I
A
L
K
N
D
E
Nematode Worm
Caenorhab. elegans
Q9N3B0
168
18950
A19
I
V
V
A
S
A
A
A
P
Q
C
E
V
C
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.9
59.8
94.4
N.A.
97.2
97.7
N.A.
75
N.A.
N.A.
69.4
N.A.
49.7
48
46.9
N.A.
Protein Similarity:
100
72.7
73.2
97.2
N.A.
97.7
98.3
N.A.
81.1
N.A.
N.A.
85.5
N.A.
68.7
70.9
63.1
N.A.
P-Site Identity:
100
93.3
13.3
86.6
N.A.
93.3
93.3
N.A.
6.6
N.A.
N.A.
33.3
N.A.
26.6
13.3
0
N.A.
P-Site Similarity:
100
100
26.6
86.6
N.A.
93.3
93.3
N.A.
6.6
N.A.
N.A.
46.6
N.A.
46.6
46.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
19
10
10
10
10
10
19
0
55
0
0
0
10
0
% A
% Cys:
0
0
0
0
10
0
10
0
0
0
10
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
28
0
10
0
0
0
10
10
64
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
10
10
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
10
28
10
10
10
0
0
10
55
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
10
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
28
0
0
10
% K
% Leu:
28
55
10
19
46
0
0
0
19
10
73
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
0
0
0
10
46
0
0
10
0
0
10
46
10
0
% P
% Gln:
0
0
0
10
0
19
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
46
0
10
46
10
0
0
% R
% Ser:
0
10
55
0
10
10
0
55
0
10
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
19
0
0
10
0
0
0
0
0
% T
% Val:
19
10
10
55
0
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _