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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANF
All Species:
37.27
Human Site:
Y73
Identified Species:
82
UniProt:
P55145
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55145
NP_006001.2
179
20257
Y73
G
K
E
N
R
L
C
Y
Y
I
G
A
T
D
D
Chimpanzee
Pan troglodytes
XP_001169644
246
27914
Y140
G
K
E
N
R
L
C
Y
Y
I
G
A
T
D
D
Rhesus Macaque
Macaca mulatta
XP_001088321
187
20989
Y83
G
K
E
N
R
L
C
Y
Y
L
G
A
T
K
D
Dog
Lupus familis
XP_850540
179
20362
Y73
G
K
E
N
R
L
C
Y
Y
I
G
A
T
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXI5
179
20355
Y73
G
K
E
N
R
L
C
Y
Y
I
G
A
T
D
D
Rat
Rattus norvegicus
P0C5H9
179
20369
Y73
G
K
E
N
R
L
C
Y
Y
I
G
A
T
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506741
196
22383
Y90
G
K
E
N
R
L
C
Y
Y
I
G
A
T
S
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666400
180
20155
Y74
G
K
E
N
R
F
C
Y
Y
I
G
A
T
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ63
173
20118
Y73
N
K
E
H
R
F
C
Y
Y
L
G
G
L
E
E
Honey Bee
Apis mellifera
XP_625023
175
20050
Y72
S
K
E
N
R
F
C
Y
Y
L
G
G
L
E
E
Nematode Worm
Caenorhab. elegans
Q9N3B0
168
18950
F67
N
K
E
N
K
F
C
F
Y
I
G
A
L
P
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.9
59.8
94.4
N.A.
97.2
97.7
N.A.
75
N.A.
N.A.
69.4
N.A.
49.7
48
46.9
N.A.
Protein Similarity:
100
72.7
73.2
97.2
N.A.
97.7
98.3
N.A.
81.1
N.A.
N.A.
85.5
N.A.
68.7
70.9
63.1
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
86.6
N.A.
46.6
53.3
53.3
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
86.6
N.A.
73.3
73.3
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
82
0
0
0
% A
% Cys:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
73
% D
% Glu:
0
0
100
0
0
0
0
0
0
0
0
0
0
19
28
% E
% Phe:
0
0
0
0
0
37
0
10
0
0
0
0
0
0
0
% F
% Gly:
73
0
0
0
0
0
0
0
0
0
100
19
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
73
0
0
0
0
0
% I
% Lys:
0
100
0
0
10
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
64
0
0
0
28
0
0
28
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
91
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
91
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
73
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
91
100
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _