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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLLT6 All Species: 11.52
Human Site: S435 Identified Species: 25.33
UniProt: P55198 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55198 NP_005928.2 1093 112076 S435 K S P H V T G S G A S A G T H
Chimpanzee Pan troglodytes XP_511438 1140 117178 S482 K S P H V T G S G A S A G T H
Rhesus Macaque Macaca mulatta XP_001083126 1096 112258 S438 K S P H V T G S G A S A G T H
Dog Lupus familis XP_850714 1066 109714 P432 P A P A E E T P E T G L K E K
Cat Felis silvestris
Mouse Mus musculus O54826 1068 112946 Y450 S S F P T A G Y K R A Q T S G
Rat Rattus norvegicus XP_239329 1051 107603 P419 L G P A E E A P E T T L K E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510168 1032 109035 H434 K G S K Q S K H G P G R P K G
Chicken Gallus gallus XP_418117 880 92966 G312 N K D P I S H G G G V L R A V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122343 521 55451
Nematode Worm Caenorhab. elegans P34447 867 92171 S299 S S V A Q D P S P P L T I N K
Sea Urchin Strong. purpuratus XP_794974 1041 109191 S445 S G A P G S T S T M V D V E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.7 98.9 94.2 N.A. 38.5 89.5 N.A. 32.8 54.7 N.A. N.A. N.A. N.A. 26.2 25.4 26.8
Protein Similarity: 100 92.1 99.3 95.6 N.A. 51.7 91.6 N.A. 46.9 62.5 N.A. N.A. N.A. N.A. 37.4 40.2 39.6
P-Site Identity: 100 100 100 6.6 N.A. 13.3 6.6 N.A. 13.3 6.6 N.A. N.A. N.A. N.A. 0 13.3 6.6
P-Site Similarity: 100 100 100 13.3 N.A. 26.6 13.3 N.A. 20 20 N.A. N.A. N.A. N.A. 0 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 28 0 10 10 0 0 28 10 28 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 10 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 19 19 0 0 19 0 0 0 0 28 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 28 0 0 10 0 37 10 46 10 19 0 28 0 19 % G
% His: 0 0 0 28 0 0 10 10 0 0 0 0 0 0 28 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 37 10 0 10 0 0 10 0 10 0 0 0 19 10 37 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 10 28 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 10 0 46 28 0 0 10 19 10 19 0 0 10 0 0 % P
% Gln: 0 0 0 0 19 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 10 10 0 0 % R
% Ser: 28 46 10 0 0 28 0 46 0 0 28 0 0 10 0 % S
% Thr: 0 0 0 0 10 28 19 0 10 19 10 10 10 28 0 % T
% Val: 0 0 10 0 28 0 0 0 0 0 19 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _