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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ELL
All Species:
10.91
Human Site:
S446
Identified Species:
24
UniProt:
P55199
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55199
NP_006523.1
621
68265
S446
P
H
G
S
P
S
R
S
K
P
K
K
K
S
K
Chimpanzee
Pan troglodytes
XP_001134697
525
55426
D362
L
E
P
P
R
A
H
D
P
L
A
D
V
S
N
Rhesus Macaque
Macaca mulatta
XP_001115395
573
63224
K410
K
S
K
K
H
K
D
K
E
R
A
S
E
D
R
Dog
Lupus familis
XP_541936
613
67582
S441
P
H
G
S
S
S
R
S
K
S
K
K
K
S
K
Cat
Felis silvestris
Mouse
Mus musculus
O08856
602
67102
S433
T
S
S
S
H
T
H
S
R
P
K
K
K
S
K
Rat
Rattus norvegicus
Q6P6T5
523
59168
S360
Q
E
I
P
L
T
L
S
V
D
D
F
R
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512162
647
73077
K466
D
K
H
S
A
S
H
K
K
S
K
K
K
S
K
Chicken
Gallus gallus
NP_001012865
610
68151
S439
Y
V
K
S
K
K
K
S
K
K
H
K
D
K
E
Frog
Xenopus laevis
Q9PUN1
493
55093
L330
I
A
E
E
E
L
P
L
K
E
D
Y
G
M
S
Zebra Danio
Brachydanio rerio
NP_956001
633
70945
G447
T
T
Q
P
S
L
H
G
K
S
K
K
K
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393419
769
85197
S560
S
A
S
S
F
S
G
S
S
N
G
I
L
A
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.3
88.2
88.7
N.A.
82.2
21.2
N.A.
44.9
70.2
20.9
55.2
N.A.
N.A.
28.7
N.A.
N.A.
Protein Similarity:
100
65.5
90.1
92.1
N.A.
87.1
35.7
N.A.
60.7
81.4
35.9
68.7
N.A.
N.A.
45.1
N.A.
N.A.
P-Site Identity:
100
6.6
0
86.6
N.A.
53.3
6.6
N.A.
53.3
26.6
6.6
40
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
13.3
20
86.6
N.A.
66.6
20
N.A.
53.3
40
6.6
40
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
10
10
0
0
0
0
19
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
10
0
10
19
10
10
10
10
% D
% Glu:
0
19
10
10
10
0
0
0
10
10
0
0
10
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
19
0
0
0
10
10
0
0
10
0
10
0
0
% G
% His:
0
19
10
0
19
0
37
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
10
10
19
10
10
19
10
19
55
10
46
55
46
10
46
% K
% Leu:
10
0
0
0
10
19
10
10
0
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
19
0
10
28
10
0
10
0
10
19
0
0
0
0
10
% P
% Gln:
10
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
10
0
19
0
10
10
0
0
10
0
10
% R
% Ser:
10
19
19
55
19
37
0
55
10
28
0
10
0
55
10
% S
% Thr:
19
10
0
0
0
19
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _