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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ELL All Species: 8.48
Human Site: T493 Identified Species: 18.67
UniProt: P55199 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55199 NP_006523.1 621 68265 T493 D T P G L N G T C S V S S V P
Chimpanzee Pan troglodytes XP_001134697 525 55426 D399 L G L P L L T D C A Q P S R P
Rhesus Macaque Macaca mulatta XP_001115395 573 63224 S447 P G V N G S C S V S S V P T S
Dog Lupus familis XP_541936 613 67582 T485 D A P G L N G T C N S S S V P
Cat Felis silvestris
Mouse Mus musculus O08856 602 67102 N474 P P D A P G L N G A C D N E P
Rat Rattus norvegicus Q6P6T5 523 59168 D397 K A K R T D P D H Y E T D Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512162 647 73077 V519 L N E G R V Q V C S A S T D P
Chicken Gallus gallus NP_001012865 610 68151 G482 S E P Q D A P G L N G T C N N
Frog Xenopus laevis Q9PUN1 493 55093 D367 K P R R S D L D T N E G G Y N
Zebra Danio Brachydanio rerio NP_956001 633 70945 T505 K S T G L N G T C N S S S I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393419 769 85197 C620 N T V S T S S C A L E L P E S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.3 88.2 88.7 N.A. 82.2 21.2 N.A. 44.9 70.2 20.9 55.2 N.A. N.A. 28.7 N.A. N.A.
Protein Similarity: 100 65.5 90.1 92.1 N.A. 87.1 35.7 N.A. 60.7 81.4 35.9 68.7 N.A. N.A. 45.1 N.A. N.A.
P-Site Identity: 100 26.6 6.6 80 N.A. 6.6 0 N.A. 33.3 6.6 0 60 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 33.3 20 86.6 N.A. 20 13.3 N.A. 40 20 13.3 80 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 10 0 10 0 0 10 19 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 10 46 0 10 0 10 0 0 % C
% Asp: 19 0 10 0 10 19 0 28 0 0 0 10 10 10 0 % D
% Glu: 0 10 10 0 0 0 0 0 0 0 28 0 0 19 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 0 37 10 10 28 10 10 0 10 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 28 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 19 0 10 0 37 10 19 0 10 10 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 10 0 28 0 10 0 37 0 0 10 10 19 % N
% Pro: 19 19 28 10 10 0 19 0 0 0 0 10 19 0 55 % P
% Gln: 0 0 0 10 0 0 10 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 10 19 10 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 10 10 0 10 10 19 10 10 0 28 28 37 37 0 19 % S
% Thr: 0 19 10 0 19 0 10 28 10 0 0 19 10 10 10 % T
% Val: 0 0 19 0 0 10 0 10 10 0 10 10 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _