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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRPF1 All Species: 10.91
Human Site: S841 Identified Species: 21.82
UniProt: P55201 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55201 NP_001003694.1 1214 137499 S841 P E R H G P S S R G S L T P H
Chimpanzee Pan troglodytes XP_001139344 1189 133195 E795 D K S P P K L E P S D A L P L
Rhesus Macaque Macaca mulatta XP_001093928 1214 137524 S841 P E R H G P S S R G S L T P H
Dog Lupus familis XP_861729 1214 137470 S841 P D R H G P T S R S S L T P H
Cat Felis silvestris
Mouse Mus musculus Q6IE82 823 93436 E480 M H L R Q D L E R V R N L C Y
Rat Rattus norvegicus XP_001054156 1212 137277 G839 P E R H G P S G R G N L T P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026635 1218 137679 S844 G L E R H S S S A R G V L Q S
Frog Xenopus laevis Q6GQJ2 827 94374 R484 K E Q D V L I R R L Q L F T H
Zebra Danio Brachydanio rerio Q803A0 829 94529 L486 Q E V L L R R L R L F T H L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20318 1042 117625 S699 P G S S K K S S R K R G I Q D
Sea Urchin Strong. purpuratus XP_001190303 1270 142629 V860 G G A V A R S V R T M S D P Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12311 748 86011 R405 Y H V T C A R R A G L Y M S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.7 99.8 99.1 N.A. 23.2 98.1 N.A. N.A. 91.1 23.7 23.6 N.A. N.A. N.A. 22.5 55
Protein Similarity: 100 64.1 99.8 99.4 N.A. 37.4 99 N.A. N.A. 94.4 37.4 37.8 N.A. N.A. N.A. 40.2 68.5
P-Site Identity: 100 6.6 100 80 N.A. 6.6 86.6 N.A. N.A. 13.3 26.6 13.3 N.A. N.A. N.A. 26.6 20
P-Site Similarity: 100 13.3 100 93.3 N.A. 13.3 93.3 N.A. N.A. 20 33.3 13.3 N.A. N.A. N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 32.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 9 9 0 0 17 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 9 9 0 9 0 9 0 0 0 0 9 0 9 0 9 % D
% Glu: 0 42 9 0 0 0 0 17 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % F
% Gly: 17 17 0 0 34 0 0 9 0 34 9 9 0 0 0 % G
% His: 0 17 0 34 9 0 0 0 0 0 0 0 9 0 42 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % I
% Lys: 9 9 0 0 9 17 0 0 0 9 0 0 0 0 9 % K
% Leu: 0 9 9 9 9 9 17 9 0 17 9 42 25 9 9 % L
% Met: 9 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % N
% Pro: 42 0 0 9 9 34 0 0 9 0 0 0 0 50 0 % P
% Gln: 9 0 9 0 9 0 0 0 0 0 9 0 0 17 9 % Q
% Arg: 0 0 34 17 0 17 17 17 75 9 17 0 0 0 9 % R
% Ser: 0 0 17 9 0 9 50 42 0 17 25 9 0 9 9 % S
% Thr: 0 0 0 9 0 0 9 0 0 9 0 9 34 9 0 % T
% Val: 0 0 17 9 9 0 0 9 0 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _