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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRPF1 All Species: 22.42
Human Site: T448 Identified Species: 44.85
UniProt: P55201 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55201 NP_001003694.1 1214 137499 T448 T A Y C D I H T P P G S A R R
Chimpanzee Pan troglodytes XP_001139344 1189 133195 I452 P T V C A P Y I P P Q R L N R
Rhesus Macaque Macaca mulatta XP_001093928 1214 137524 T448 T A Y C D I H T P P G S A R R
Dog Lupus familis XP_861729 1214 137470 T448 T A Y C D I H T P P G S A R R
Cat Felis silvestris
Mouse Mus musculus Q6IE82 823 93436 I145 Y D L D D M D I F W L Q E L N
Rat Rattus norvegicus XP_001054156 1212 137277 T447 T A Y C D I H T P P G S A R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026635 1218 137679 T455 T A Y C D I H T P P G S V R R
Frog Xenopus laevis Q6GQJ2 827 94374 L150 M D V A W L Q L I N E E F K E
Zebra Danio Brachydanio rerio Q803A0 829 94529 S152 Q I T N E E F S K M G M Q P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20318 1042 117625 H365 R F V W C P K H A P P L T D A
Sea Urchin Strong. purpuratus XP_001190303 1270 142629 T443 T A F C D I H T P A E A E K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12311 748 86011 L71 K S V Q T K E L I F K G R V T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.7 99.8 99.1 N.A. 23.2 98.1 N.A. N.A. 91.1 23.7 23.6 N.A. N.A. N.A. 22.5 55
Protein Similarity: 100 64.1 99.8 99.4 N.A. 37.4 99 N.A. N.A. 94.4 37.4 37.8 N.A. N.A. N.A. 40.2 68.5
P-Site Identity: 100 26.6 100 100 N.A. 6.6 100 N.A. N.A. 93.3 0 6.6 N.A. N.A. N.A. 6.6 53.3
P-Site Similarity: 100 33.3 100 100 N.A. 13.3 100 N.A. N.A. 93.3 13.3 20 N.A. N.A. N.A. 6.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 32.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 0 9 9 0 0 0 9 9 0 9 34 0 9 % A
% Cys: 0 0 0 59 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 9 59 0 9 0 0 0 0 0 0 9 0 % D
% Glu: 0 0 0 0 9 9 9 0 0 0 17 9 17 0 9 % E
% Phe: 0 9 9 0 0 0 9 0 9 9 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 50 9 0 0 0 % G
% His: 0 0 0 0 0 0 50 9 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 50 0 17 17 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 9 9 0 9 0 9 0 0 17 9 % K
% Leu: 0 0 9 0 0 9 0 17 0 0 9 9 9 9 9 % L
% Met: 9 0 0 0 0 9 0 0 0 9 0 9 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 9 0 0 0 9 9 % N
% Pro: 9 0 0 0 0 17 0 0 59 59 9 0 0 9 0 % P
% Gln: 9 0 0 9 0 0 9 0 0 0 9 9 9 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 9 9 42 50 % R
% Ser: 0 9 0 0 0 0 0 9 0 0 0 42 0 0 0 % S
% Thr: 50 9 9 0 9 0 0 50 0 0 0 0 9 0 9 % T
% Val: 0 0 34 0 0 0 0 0 0 0 0 0 9 9 0 % V
% Trp: 0 0 0 9 9 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 9 0 42 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _