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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRPF1
All Species:
21.21
Human Site:
Y665
Identified Species:
42.42
UniProt:
P55201
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55201
NP_001003694.1
1214
137499
Y665
P
L
S
E
V
P
D
Y
L
D
H
I
K
K
P
Chimpanzee
Pan troglodytes
XP_001139344
1189
133195
V653
T
V
F
Y
R
A
A
V
R
L
R
D
Q
G
G
Rhesus Macaque
Macaca mulatta
XP_001093928
1214
137524
Y665
P
L
S
E
V
P
D
Y
L
D
H
I
K
K
P
Dog
Lupus familis
XP_861729
1214
137470
Y665
P
L
S
E
V
P
D
Y
L
D
H
I
K
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6IE82
823
93436
E341
F
H
V
T
C
A
F
E
H
G
L
E
M
K
T
Rat
Rattus norvegicus
XP_001054156
1212
137277
Y664
P
L
S
E
V
P
D
Y
L
D
H
I
K
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026635
1218
137679
Y670
P
L
S
E
V
P
D
Y
L
D
H
I
K
K
P
Frog
Xenopus laevis
Q6GQJ2
827
94374
E345
C
A
F
D
H
G
L
E
M
K
T
I
L
T
Q
Zebra Danio
Brachydanio rerio
Q803A0
829
94529
T347
L
K
M
N
T
I
L
T
E
A
D
E
V
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20318
1042
117625
A560
L
K
D
M
S
E
K
A
A
S
G
K
Y
S
T
Sea Urchin
Strong. purpuratus
XP_001190303
1270
142629
Y651
A
V
D
E
A
P
D
Y
Y
D
V
I
T
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12311
748
86011
C266
G
L
S
M
D
Q
A
C
A
V
C
L
G
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.7
99.8
99.1
N.A.
23.2
98.1
N.A.
N.A.
91.1
23.7
23.6
N.A.
N.A.
N.A.
22.5
55
Protein Similarity:
100
64.1
99.8
99.4
N.A.
37.4
99
N.A.
N.A.
94.4
37.4
37.8
N.A.
N.A.
N.A.
40.2
68.5
P-Site Identity:
100
0
100
100
N.A.
6.6
100
N.A.
N.A.
100
6.6
6.6
N.A.
N.A.
N.A.
0
53.3
P-Site Similarity:
100
13.3
100
100
N.A.
6.6
100
N.A.
N.A.
100
20
6.6
N.A.
N.A.
N.A.
0
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
17
17
9
17
9
0
0
0
0
0
% A
% Cys:
9
0
0
0
9
0
0
9
0
0
9
0
0
0
0
% C
% Asp:
0
0
17
9
9
0
50
0
0
50
9
9
0
0
9
% D
% Glu:
0
0
0
50
0
9
0
17
9
0
0
17
0
0
0
% E
% Phe:
9
0
17
0
0
0
9
0
0
0
0
0
0
0
9
% F
% Gly:
9
0
0
0
0
9
0
0
0
9
9
0
9
9
9
% G
% His:
0
9
0
0
9
0
0
0
9
0
42
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
59
0
0
0
% I
% Lys:
0
17
0
0
0
0
9
0
0
9
0
9
42
67
0
% K
% Leu:
17
50
0
0
0
0
17
0
42
9
9
9
9
0
0
% L
% Met:
0
0
9
17
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
42
0
0
0
0
50
0
0
0
0
0
0
0
0
50
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
9
% Q
% Arg:
0
0
0
0
9
0
0
0
9
0
9
0
0
0
0
% R
% Ser:
0
0
50
0
9
0
0
0
0
9
0
0
0
9
0
% S
% Thr:
9
0
0
9
9
0
0
9
0
0
9
0
9
17
17
% T
% Val:
0
17
9
0
42
0
0
9
0
9
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
50
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _