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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAP1L1 All Species: 40.91
Human Site: S246 Identified Species: 90
UniProt: P55209 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55209 NP_004528.1 391 45374 S246 P D D S D P F S F D G P E I M
Chimpanzee Pan troglodytes XP_001161251 368 42743 S246 P D D S D P F S F D G P E I M
Rhesus Macaque Macaca mulatta XP_001103652 391 45356 S246 P D D S D P F S F D G P E I M
Dog Lupus familis XP_864595 391 45346 S246 P D D S D P F S F D G P E I M
Cat Felis silvestris
Mouse Mus musculus P28656 391 45327 S246 P D D S D P F S F D G P E I M
Rat Rattus norvegicus Q9Z2G8 390 45285 S245 P D D S D P F S F D G P E I M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514695 387 44667 S241 P D D S D P F S F D G P E I M
Chicken Gallus gallus XP_416106 393 45340 S247 P D D S D P F S F D G P E I M
Frog Xenopus laevis Q7ZY81 393 45498 S247 P D E S D P F S F D G P E I M
Zebra Danio Brachydanio rerio NP_958475 385 44459 S238 P D E S D P F S F D G P E I M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25293 417 47866 I265 L G Y S G D F I Y D H A E G C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 99.7 99.4 N.A. 98.2 97.1 N.A. 89.5 92.3 88 82.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 93.3 100 99.7 N.A. 100 98.9 N.A. 94.1 96.4 95.4 91.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 93.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 56.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 91 73 0 91 10 0 0 0 100 0 0 0 0 0 % D
% Glu: 0 0 19 0 0 0 0 0 0 0 0 0 100 0 0 % E
% Phe: 0 0 0 0 0 0 100 0 91 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 10 0 0 0 0 0 91 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 0 91 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 91 0 0 0 0 91 0 0 0 0 0 91 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 100 0 0 0 91 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _