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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP9
All Species:
19.09
Human Site:
S382
Identified Species:
35
UniProt:
P55211
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55211
NP_001220.2
416
46281
S382
A
H
S
E
D
L
Q
S
L
L
L
R
V
A
N
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
F247
N
R
K
V
A
T
E
F
E
S
F
S
F
D
A
Rhesus Macaque
Macaca mulatta
XP_001082859
416
46192
S382
A
H
S
E
D
L
Q
S
L
L
L
R
V
A
D
Dog
Lupus familis
XP_865164
414
45235
T381
A
H
A
E
D
L
Q
T
L
L
L
R
V
A
N
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
D405
A
C
D
M
H
V
A
D
M
L
V
K
V
N
A
Rat
Rattus norvegicus
P55215
452
50709
D405
A
C
D
M
H
V
A
D
M
L
V
K
V
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520982
366
40213
T332
A
H
T
E
D
L
L
T
L
L
L
R
V
S
N
Chicken
Gallus gallus
Q98943
424
47941
D376
S
R
D
T
H
V
A
D
M
L
V
K
V
N
R
Frog
Xenopus laevis
P55866
282
32106
H252
Q
I
L
T
C
V
N
H
M
V
A
L
D
F
E
Zebra Danio
Brachydanio rerio
NP_001007405
436
48445
T397
A
I
T
D
D
L
V
T
M
L
M
L
V
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
M293
S
N
V
P
A
T
P
M
M
D
R
Q
K
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
E456
A
K
D
M
D
V
V
E
L
L
T
E
V
N
K
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
S396
A
G
E
E
D
L
L
S
M
I
T
M
V
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
93.9
76.9
N.A.
28.9
28.3
N.A.
52.8
31.1
22.6
47.2
N.A.
22.1
N.A.
21.6
32.2
Protein Similarity:
100
35.8
96.8
84.1
N.A.
46.9
46.2
N.A.
65.6
48.3
38.7
64.2
N.A.
35.8
N.A.
37.5
51
P-Site Identity:
100
0
93.3
86.6
N.A.
20
20
N.A.
73.3
13.3
0
33.3
N.A.
0
N.A.
33.3
40
P-Site Similarity:
100
6.6
100
100
N.A.
46.6
46.6
N.A.
93.3
46.6
20
73.3
N.A.
26.6
N.A.
40
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
8
0
16
0
24
0
0
0
8
0
0
24
24
% A
% Cys:
0
16
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
31
8
54
0
0
24
0
8
0
0
8
8
16
% D
% Glu:
0
0
8
39
0
0
8
8
8
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
8
8
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
31
0
0
24
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
0
24
8
0
8
% K
% Leu:
0
0
8
0
0
47
16
0
39
70
31
16
0
0
0
% L
% Met:
0
0
0
24
0
0
0
8
54
0
8
8
0
0
0
% M
% Asn:
8
8
0
0
0
0
8
0
0
0
0
0
0
47
24
% N
% Pro:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
24
0
0
0
0
8
0
8
0
% Q
% Arg:
0
16
0
0
0
0
0
0
0
0
8
31
0
0
8
% R
% Ser:
16
0
16
0
0
0
0
24
0
8
0
8
0
8
0
% S
% Thr:
0
0
16
16
0
16
0
24
0
0
16
0
0
0
0
% T
% Val:
0
0
8
8
0
39
16
0
0
8
24
0
77
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _