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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP6
All Species:
27.27
Human Site:
Y128
Identified Species:
50
UniProt:
P55212
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55212
NP_001217.2
293
33310
Y128
H
G
E
G
N
H
I
Y
A
Y
D
A
K
I
E
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
F128
H
G
E
E
G
I
I
F
G
T
N
G
P
V
D
Rhesus Macaque
Macaca mulatta
XP_001083044
277
31383
F128
H
G
E
E
G
I
I
F
G
T
N
G
P
L
D
Dog
Lupus familis
XP_545022
293
33413
Y128
H
G
E
G
N
H
I
Y
A
Y
D
A
K
I
E
Cat
Felis silvestris
Mouse
Mus musculus
O08738
276
31577
Y111
H
G
E
G
N
H
V
Y
A
Y
D
A
K
I
E
Rat
Rattus norvegicus
O35397
277
31537
Y111
H
G
E
G
N
H
I
Y
A
Y
D
A
K
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506240
334
37612
Y169
H
G
Q
G
N
H
V
Y
A
Y
N
G
K
I
D
Chicken
Gallus gallus
Q98943
424
47941
G256
G
V
E
G
G
V
Y
G
T
D
G
K
L
L
Q
Frog
Xenopus laevis
P55866
282
32106
L129
S
S
F
V
C
A
I
L
S
H
G
E
E
D
G
Zebra Danio
Brachydanio rerio
NP_001018333
298
33677
Y138
H
G
E
N
G
H
V
Y
A
N
D
G
Q
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01382
339
37345
Y176
H
G
E
M
G
Y
I
Y
A
K
D
T
Q
Y
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
G323
G
E
E
N
V
I
I
G
V
D
D
I
P
I
S
Sea Urchin
Strong. purpuratus
XP_789185
329
37214
Y165
H
G
D
D
G
I
L
Y
A
R
D
S
T
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.5
37.5
89.7
N.A.
85.3
83.2
N.A.
69.1
22.1
38.2
64.7
N.A.
34.5
N.A.
20
42.5
Protein Similarity:
100
52.5
53.2
94.8
N.A.
90.4
88.7
N.A.
77.8
38.2
54.9
75.1
N.A.
50.1
N.A.
34.1
59.5
P-Site Identity:
100
26.6
26.6
100
N.A.
93.3
100
N.A.
66.6
13.3
6.6
60
N.A.
46.6
N.A.
26.6
33.3
P-Site Similarity:
100
53.3
53.3
100
N.A.
100
100
N.A.
93.3
26.6
26.6
73.3
N.A.
66.6
N.A.
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
62
0
0
31
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
16
62
0
0
8
31
% D
% Glu:
0
8
77
16
0
0
0
0
0
0
0
8
8
0
39
% E
% Phe:
0
0
8
0
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
16
77
0
47
47
0
0
16
16
0
16
31
0
0
8
% G
% His:
77
0
0
0
0
47
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
31
62
0
0
0
0
8
0
54
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
8
39
0
8
% K
% Leu:
0
0
0
0
0
0
8
8
0
0
0
0
8
24
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
39
0
0
0
0
8
24
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
16
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
8
0
0
0
0
0
0
8
0
0
8
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
8
16
0
8
8
0
0
% T
% Val:
0
8
0
8
8
8
24
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
62
0
39
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _