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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP6
All Species:
13.64
Human Site:
Y37
Identified Species:
25
UniProt:
P55212
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55212
NP_001217.2
293
33310
Y37
M
F
D
P
A
E
K
Y
K
M
D
H
R
R
R
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
M39
S
L
D
N
S
Y
K
M
D
Y
P
E
M
G
L
Rhesus Macaque
Macaca mulatta
XP_001083044
277
31383
M39
S
L
E
N
S
Y
K
M
D
Y
P
E
M
G
L
Dog
Lupus familis
XP_545022
293
33413
Y37
M
F
D
P
E
E
K
Y
K
M
D
H
K
R
R
Cat
Felis silvestris
Mouse
Mus musculus
O08738
276
31577
R37
A
L
I
F
N
H
E
R
F
F
W
H
L
T
L
Rat
Rattus norvegicus
O35397
277
31537
R37
A
L
I
F
N
H
E
R
F
F
W
H
L
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506240
334
37612
Y78
T
F
D
P
A
A
K
Y
K
M
E
Y
K
R
R
Chicken
Gallus gallus
Q98943
424
47941
Y111
I
A
T
L
E
Q
R
Y
G
S
N
L
P
L
P
Frog
Xenopus laevis
P55866
282
32106
R38
C
D
L
K
D
I
E
R
K
T
K
F
A
H
L
Zebra Danio
Brachydanio rerio
NP_001018333
298
33677
E46
F
S
M
D
P
N
Q
E
Y
D
M
N
H
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01382
339
37345
Y86
T
D
R
H
A
A
E
Y
N
M
R
H
K
N
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
Y235
V
F
D
E
K
T
M
Y
R
N
F
S
S
P
R
Sea Urchin
Strong. purpuratus
XP_789185
329
37214
L60
T
F
R
F
P
G
F
L
E
S
L
T
N
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.5
37.5
89.7
N.A.
85.3
83.2
N.A.
69.1
22.1
38.2
64.7
N.A.
34.5
N.A.
20
42.5
Protein Similarity:
100
52.5
53.2
94.8
N.A.
90.4
88.7
N.A.
77.8
38.2
54.9
75.1
N.A.
50.1
N.A.
34.1
59.5
P-Site Identity:
100
13.3
6.6
86.6
N.A.
6.6
6.6
N.A.
66.6
6.6
6.6
6.6
N.A.
33.3
N.A.
26.6
6.6
P-Site Similarity:
100
20
20
93.3
N.A.
13.3
13.3
N.A.
86.6
33.3
13.3
26.6
N.A.
46.6
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
24
16
0
0
0
0
0
0
8
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
39
8
8
0
0
0
16
8
16
0
0
0
8
% D
% Glu:
0
0
8
8
16
16
31
8
8
0
8
16
0
8
0
% E
% Phe:
8
39
0
24
0
0
8
0
16
16
8
8
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
8
0
0
0
0
16
0
% G
% His:
0
0
0
8
0
16
0
0
0
0
0
39
8
8
0
% H
% Ile:
8
0
16
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
8
0
39
0
31
0
8
0
24
8
0
% K
% Leu:
0
31
8
8
0
0
0
8
0
0
8
8
16
8
39
% L
% Met:
16
0
8
0
0
0
8
16
0
31
8
0
16
0
0
% M
% Asn:
0
0
0
16
16
8
0
0
8
8
8
8
8
8
0
% N
% Pro:
0
0
0
24
16
0
0
0
0
0
16
0
8
8
8
% P
% Gln:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
16
0
0
0
8
24
8
0
8
0
8
24
47
% R
% Ser:
16
8
0
0
16
0
0
0
0
16
0
8
8
0
0
% S
% Thr:
24
0
8
0
0
8
0
0
0
8
0
8
0
8
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% W
% Tyr:
0
0
0
0
0
16
0
47
8
16
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _