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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADK All Species: 39.09
Human Site: Y77 Identified Species: 78.18
UniProt: P55263 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55263 NP_001114.2 362 40545 Y77 V K K F K V E Y H A G G S T Q
Chimpanzee Pan troglodytes XP_001148292 362 40500 Y77 V K K F K V E Y H A G G S T Q
Rhesus Macaque Macaca mulatta XP_001098242 362 40499 Y77 V K K F K V E Y H A G G S T Q
Dog Lupus familis XP_536396 362 40543 Y77 V K K F K V E Y H A G G S T Q
Cat Felis silvestris
Mouse Mus musculus P55264 361 40130 Y76 V K K F K V E Y H A G G S T Q
Rat Rattus norvegicus Q64640 361 40115 Y76 V K K F K V E Y H A G G S T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006501 359 40062 Y74 V K K F K V E Y H A G G S T Q
Frog Xenopus laevis NP_001086357 361 40348 Y76 V K K F N V E Y H A G G S T Q
Zebra Danio Brachydanio rerio NP_997956 359 40255 Y74 V K K F K V E Y R A G G A T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002312012 341 37394 F58 A S K Y T V E F I A G G A T Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LZG0 345 37828 Y62 S S K F N V E Y I A G G A T Q
Baker's Yeast Sacchar. cerevisiae P47143 340 36354 L60 L Q M P E T K L V A G G A A Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 92.8 N.A. 91.4 90.6 N.A. N.A. 84.2 80.1 77.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 100 97.2 N.A. 97.2 96.9 N.A. N.A. 93 90.6 88.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 93.3 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 93.3 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 56 N.A. N.A. 53.8 38.6 N.A.
Protein Similarity: 73.2 N.A. N.A. 71.8 57.7 N.A.
P-Site Identity: 53.3 N.A. N.A. 66.6 26.6 N.A.
P-Site Similarity: 73.3 N.A. N.A. 73.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 100 0 0 34 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 92 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 84 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 100 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % I
% Lys: 0 75 92 0 67 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 100 % Q
% Arg: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 9 17 0 0 0 0 0 0 0 0 0 0 67 0 0 % S
% Thr: 0 0 0 0 9 9 0 0 0 0 0 0 0 92 0 % T
% Val: 75 0 0 0 0 92 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 84 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _