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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LAMB2 All Species: 39.09
Human Site: Y621 Identified Species: 71.67
UniProt: P55268 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55268 NP_002283.3 1798 195981 Y621 S V P K A M D Y D L L L R L E
Chimpanzee Pan troglodytes XP_001165567 1808 200224 Y632 N I P Y S M E Y D I L I R Y E
Rhesus Macaque Macaca mulatta XP_001109982 1797 195849 Y620 S V P K A M D Y D L L L R L E
Dog Lupus familis XP_533831 1801 195801 Y624 S V P R A M D Y D L L L R L E
Cat Felis silvestris
Mouse Mus musculus Q61292 1799 196334 Y624 S L P R A M D Y D L L L R W E
Rat Rattus norvegicus P15800 1801 196455 Y624 S L P R A M D Y D L L L R W E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506606 1485 161563 G446 E S L T P A K G S P A E A C A
Chicken Gallus gallus
Frog Xenopus laevis NP_001088164 1783 197665 Y610 N I P Y S M E Y D V I I R Y E
Zebra Danio Brachydanio rerio Q8JHV6 1827 203534 Y706 N I P A T L D Y Y V V V R Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11046 1788 198315 Y630 D I P R S M P Y D A V I R Y Q
Honey Bee Apis mellifera XP_001122457 1816 202931 Y659 D I R K S L W Y D I I V R Y E
Nematode Worm Caenorhab. elegans Q18823 1535 170219 I496 F C F G H S S I C N T A D G Y
Sea Urchin Strong. purpuratus XP_787259 1671 184983 Y610 N L P M S G N Y D L I L R Y E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50 96.2 90.8 N.A. 88.3 88 N.A. 57 N.A. 59.1 38.7 N.A. 39.9 40.7 25.8 40.8
Protein Similarity: 100 67.8 97.4 94.6 N.A. 93.2 92.9 N.A. 66.9 N.A. 75.4 55.7 N.A. 55.7 57.2 40.6 57.6
P-Site Identity: 100 46.6 100 93.3 N.A. 80 80 N.A. 0 N.A. 40 33.3 N.A. 33.3 33.3 0 46.6
P-Site Similarity: 100 86.6 100 100 N.A. 93.3 93.3 N.A. 0 N.A. 86.6 73.3 N.A. 73.3 73.3 0 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 39 8 0 0 0 8 8 8 8 0 8 % A
% Cys: 0 8 0 0 0 0 0 0 8 0 0 0 0 8 0 % C
% Asp: 16 0 0 0 0 0 47 0 77 0 0 0 8 0 0 % D
% Glu: 8 0 0 0 0 0 16 0 0 0 0 8 0 0 77 % E
% Phe: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 8 0 8 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 39 0 0 0 0 0 8 0 16 24 24 0 0 0 % I
% Lys: 0 0 0 24 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 24 8 0 0 16 0 0 0 47 47 47 0 24 0 % L
% Met: 0 0 0 8 0 62 0 0 0 0 0 0 0 0 0 % M
% Asn: 31 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 77 0 8 0 8 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 8 31 0 0 0 0 0 0 0 0 85 0 0 % R
% Ser: 39 8 0 0 39 8 8 0 8 0 0 0 0 0 0 % S
% Thr: 0 0 0 8 8 0 0 0 0 0 8 0 0 0 0 % T
% Val: 0 24 0 0 0 0 0 0 0 16 16 16 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 16 0 % W
% Tyr: 0 0 0 16 0 0 0 85 8 0 0 0 0 47 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _