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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDH8 All Species: 31.52
Human Site: Y749 Identified Species: 77.04
UniProt: P55286 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55286 NP_001787.2 799 88253 Y749 D S I Q I Y G Y E G R G S V A
Chimpanzee Pan troglodytes XP_511010 800 88238 Y750 D S I Q I Y G Y E G R G S V A
Rhesus Macaque Macaca mulatta XP_001104286 799 88235 Y749 D S I Q I Y G Y E G R G S V A
Dog Lupus familis XP_546896 799 87070 Y749 D S I Q V Y G Y E G R G S A A
Cat Felis silvestris
Mouse Mus musculus P97291 799 88182 Y749 D S I Q I Y G Y E G R G S V A
Rat Rattus norvegicus O54800 799 88315 Y749 D S I Q I Y G Y E G R G S V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509783 801 88397 Y750 D S I Q I Y G Y E G R G S V A
Chicken Gallus gallus O93319 792 87554 Y741 D S I Q I Y G Y E G R G S V A
Frog Xenopus laevis Q91838 790 88487 F740 D S L Q T Y M F E G E G S V A
Zebra Danio Brachydanio rerio XP_001919165 633 70434 E584 S I Q I Y G Y E G R G S I A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.8 92.4 N.A. 96.8 97.3 N.A. 64.6 66.3 53.6 61.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 100 95.8 N.A. 98.6 98.7 N.A. 79.2 79.9 71.8 69.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 100 100 N.A. 100 100 66.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 100 100 80 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 90 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 90 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 80 0 10 90 10 90 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 80 10 70 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 90 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 80 0 0 0 0 % R
% Ser: 10 90 0 0 0 0 0 0 0 0 0 10 90 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 0 0 80 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 90 10 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _