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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPD52
All Species:
15.76
Human Site:
S176
Identified Species:
34.67
UniProt:
P55327
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55327
NP_001020423.1
224
24327
S176
K
N
S
P
T
F
K
S
F
E
E
K
V
E
N
Chimpanzee
Pan troglodytes
XP_001162922
360
38462
S312
R
N
S
P
T
F
K
S
F
E
E
K
V
E
N
Rhesus Macaque
Macaca mulatta
XP_001107364
316
33853
S243
R
S
H
S
I
G
Y
S
I
R
H
S
I
S
M
Dog
Lupus familis
XP_535110
251
27628
S203
R
N
S
P
T
F
K
S
F
E
E
K
V
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q62393
224
24294
S175
K
N
S
P
T
F
K
S
F
E
E
K
V
E
N
Rat
Rattus norvegicus
Q6PCT3
220
23973
S166
S
S
Y
S
I
R
H
S
I
S
M
P
V
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517313
118
12998
Q71
R
T
S
E
T
L
S
Q
A
G
Q
K
A
S
A
Chicken
Gallus gallus
Q9I8F4
210
23235
V163
E
E
K
V
E
T
T
V
T
S
L
K
T
K
V
Frog
Xenopus laevis
NP_001086339
219
23983
K172
V
K
N
S
P
T
F
K
S
F
E
E
K
V
E
Zebra Danio
Brachydanio rerio
NP_001038486
187
20702
E140
T
P
S
F
K
S
F
E
E
K
V
E
T
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P55326
195
21268
F148
D
M
R
N
S
S
L
F
K
S
F
E
S
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.2
37.9
70.9
N.A.
83.9
25.8
N.A.
38.8
25.8
71.4
50
N.A.
N.A.
N.A.
31.7
N.A.
Protein Similarity:
100
57.7
50.6
73.7
N.A.
91.5
45
N.A.
46.8
47.7
81.2
61.1
N.A.
N.A.
N.A.
50.4
N.A.
P-Site Identity:
100
93.3
6.6
93.3
N.A.
100
13.3
N.A.
20
6.6
6.6
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
20
N.A.
33.3
20
20
20
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
0
10
10
0
0
10
10
37
46
28
0
37
10
% E
% Phe:
0
0
0
10
0
37
19
10
37
10
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
19
0
0
0
19
0
0
0
10
0
0
% I
% Lys:
19
10
10
0
10
0
37
10
10
10
0
55
10
19
10
% K
% Leu:
0
0
0
0
0
10
10
0
0
0
10
0
0
10
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
0
0
10
10
% M
% Asn:
0
37
10
10
0
0
0
0
0
0
0
0
0
0
37
% N
% Pro:
0
10
0
37
10
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% Q
% Arg:
37
0
10
0
0
10
0
0
0
10
0
0
0
0
10
% R
% Ser:
10
19
55
28
10
19
10
55
10
28
0
10
10
19
0
% S
% Thr:
10
10
0
0
46
19
10
0
10
0
0
0
19
0
0
% T
% Val:
10
0
0
10
0
0
0
10
0
0
10
0
46
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _