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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT2
All Species:
24.85
Human Site:
S105
Identified Species:
45.56
UniProt:
P55345
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55345
NP_001526.2
433
49042
S105
Q
D
E
E
Y
F
G
S
Y
G
T
L
K
L
H
Chimpanzee
Pan troglodytes
XP_001161092
433
48995
S105
Q
D
E
E
Y
F
G
S
Y
G
T
L
K
L
H
Rhesus Macaque
Macaca mulatta
XP_001096450
433
49207
S105
Q
D
E
E
Y
F
G
S
Y
G
T
L
K
L
H
Dog
Lupus familis
XP_537926
640
71811
S312
Q
D
E
E
Y
F
G
S
Y
G
T
L
K
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9R144
448
50458
S117
Q
D
E
E
Y
F
D
S
Y
G
T
L
K
L
H
Rat
Rattus norvegicus
Q63009
353
40504
D33
A
E
D
M
T
S
K
D
Y
Y
F
D
S
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513883
470
53922
S118
Q
D
E
E
Y
F
G
S
Y
G
T
L
K
L
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Q68EZ3
340
37897
Q20
E
Q
D
Q
E
Y
F
Q
C
Y
S
D
V
S
I
Zebra Danio
Brachydanio rerio
Q6NWG4
349
39232
V27
Y
F
D
S
Y
S
D
V
T
I
H
E
E
M
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786231
282
31591
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142360
403
44948
I83
T
S
T
Y
R
N
A
I
M
H
H
K
D
L
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU94
390
43875
D70
T
D
D
T
T
S
A
D
Y
Y
F
D
S
Y
S
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
S26
S
E
Q
H
Y
F
N
S
Y
D
H
Y
G
I
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.6
61.5
N.A.
77.4
29.3
N.A.
67
N.A.
30
30.7
N.A.
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
100
98.8
65.1
N.A.
84.8
48
N.A.
78.3
N.A.
43.4
45
N.A.
N.A.
N.A.
N.A.
42.4
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
100
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
20
N.A.
100
N.A.
33.3
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
30.4
N.A.
31.4
30
N.A.
Protein Similarity:
N.A.
49.4
N.A.
50.1
48.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
33.3
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
20
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
16
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
54
31
0
0
0
16
16
0
8
0
24
8
0
0
% D
% Glu:
8
16
47
47
8
0
0
0
0
0
0
8
8
0
0
% E
% Phe:
0
8
0
0
0
54
8
0
0
0
16
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
39
0
0
47
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
8
24
0
0
0
54
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
0
0
0
8
24
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
8
47
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
47
0
54
0
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
47
8
8
8
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
8
0
24
0
54
0
0
8
0
16
8
8
% S
% Thr:
16
0
8
8
16
0
0
0
8
0
47
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
62
8
0
0
70
24
0
8
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _