KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT2
All Species:
10
Human Site:
S21
Identified Species:
18.33
UniProt:
P55345
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55345
NP_001526.2
433
49042
S21
G
E
E
P
A
E
C
S
E
A
G
L
L
Q
E
Chimpanzee
Pan troglodytes
XP_001161092
433
48995
S21
G
E
E
P
A
E
C
S
E
A
G
L
L
Q
E
Rhesus Macaque
Macaca mulatta
XP_001096450
433
49207
S21
E
E
E
P
A
E
Y
S
E
A
G
L
L
Q
E
Dog
Lupus familis
XP_537926
640
71811
G228
G
E
D
H
V
E
C
G
D
Q
E
H
L
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9R144
448
50458
D21
V
I
P
V
L
E
E
D
P
V
D
Y
G
C
E
Rat
Rattus norvegicus
Q63009
353
40504
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513883
470
53922
S38
N
K
E
E
T
E
E
S
F
I
E
S
S
E
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q68EZ3
340
37897
Zebra Danio
Brachydanio rerio
Q6NWG4
349
39232
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786231
282
31591
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142360
403
44948
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU94
390
43875
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.6
61.5
N.A.
77.4
29.3
N.A.
67
N.A.
30
30.7
N.A.
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
100
98.8
65.1
N.A.
84.8
48
N.A.
78.3
N.A.
43.4
45
N.A.
N.A.
N.A.
N.A.
42.4
P-Site Identity:
100
100
86.6
46.6
N.A.
13.3
0
N.A.
20
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
60
N.A.
13.3
0
N.A.
33.3
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
30.4
N.A.
31.4
30
N.A.
Protein Similarity:
N.A.
49.4
N.A.
50.1
48.5
N.A.
P-Site Identity:
N.A.
0
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
24
0
0
0
0
24
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
24
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
0
0
0
8
8
0
8
0
0
0
0
% D
% Glu:
8
31
31
8
0
47
16
0
24
0
16
0
0
8
39
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
24
0
0
0
0
0
0
8
0
0
24
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
24
31
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
24
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
31
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
31
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
8
8
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _