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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT2
All Species:
26.36
Human Site:
Y165
Identified Species:
48.33
UniProt:
P55345
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55345
NP_001526.2
433
49042
Y165
Y
A
R
P
R
A
V
Y
A
V
E
A
S
E
M
Chimpanzee
Pan troglodytes
XP_001161092
433
48995
Y165
Y
A
R
P
K
A
V
Y
A
V
E
A
S
E
M
Rhesus Macaque
Macaca mulatta
XP_001096450
433
49207
Y165
Y
A
R
P
K
A
V
Y
A
V
E
A
S
E
M
Dog
Lupus familis
XP_537926
640
71811
Y372
Y
A
Q
P
K
A
V
Y
A
V
E
A
S
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9R144
448
50458
Y177
H
A
R
P
K
A
V
Y
A
V
E
A
S
D
M
Rat
Rattus norvegicus
Q63009
353
40504
A93
M
F
A
A
K
A
G
A
R
K
V
I
G
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513883
470
53922
Y178
H
A
Q
P
K
A
V
Y
A
V
E
A
S
E
M
Chicken
Gallus gallus
Frog
Xenopus laevis
Q68EZ3
340
37897
Y80
Q
A
G
A
T
R
V
Y
A
V
E
A
S
A
V
Zebra Danio
Brachydanio rerio
Q6NWG4
349
39232
S87
K
V
Y
A
V
E
A
S
S
I
A
D
Q
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786231
282
31591
K22
C
N
G
N
G
N
Q
K
G
G
C
S
H
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142360
403
44948
V143
N
E
L
S
D
K
V
V
V
L
H
G
R
I
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU94
390
43875
A130
L
F
C
A
K
A
G
A
A
H
V
Y
A
V
E
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
G86
H
G
A
K
H
V
I
G
V
D
M
S
S
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.6
61.5
N.A.
77.4
29.3
N.A.
67
N.A.
30
30.7
N.A.
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
100
98.8
65.1
N.A.
84.8
48
N.A.
78.3
N.A.
43.4
45
N.A.
N.A.
N.A.
N.A.
42.4
P-Site Identity:
100
93.3
93.3
86.6
N.A.
80
6.6
N.A.
80
N.A.
53.3
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
N.A.
60
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
30.4
N.A.
31.4
30
N.A.
Protein Similarity:
N.A.
49.4
N.A.
50.1
48.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
16
31
0
62
8
16
62
0
8
54
8
16
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
0
8
0
8
0
% D
% Glu:
0
8
0
0
0
8
0
0
0
0
54
0
0
39
24
% E
% Phe:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
16
0
8
0
16
8
8
8
0
8
8
0
0
% G
% His:
24
0
0
0
8
0
0
0
0
8
8
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
8
0
8
0
24
8
% I
% Lys:
8
0
0
8
54
8
0
8
0
8
0
0
0
0
0
% K
% Leu:
8
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
47
% M
% Asn:
8
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
47
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
16
0
0
0
8
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
31
0
8
8
0
0
8
0
0
0
8
0
0
% R
% Ser:
0
0
0
8
0
0
0
8
8
0
0
16
62
0
8
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
8
8
62
8
16
54
16
0
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
31
0
8
0
0
0
0
54
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _