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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC13 All Species: 41.82
Human Site: S130 Identified Species: 65.71
UniProt: P55735 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55735 NP_001129704.1 322 35541 S130 G S S D G A I S L L T Y T G E
Chimpanzee Pan troglodytes XP_516277 314 34654 S130 G S S D G A I S L L T Y T G E
Rhesus Macaque Macaca mulatta XP_001089862 325 35829 S133 G S S D G A I S L L M Y T G E
Dog Lupus familis XP_850437 322 35501 S130 G S S D G A I S L L T Y T G E
Cat Felis silvestris
Mouse Mus musculus Q9D1M0 322 35547 S130 G S S D G A I S L L T Y T G E
Rat Rattus norvegicus Q5XFW8 322 35529 S130 G S S D G A I S L L T Y T G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509095 346 38353 S155 G S S D G A I S L L S Y T G E
Chicken Gallus gallus XP_414450 435 46576 S245 G S S D G A I S L L S Y T G D
Frog Xenopus laevis Q4FZW5 360 39707 L130 P K H M G L M L A T C S A D G
Zebra Danio Brachydanio rerio Q6TGU2 364 39798 L130 P K H M G L M L T T C S A D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651977 356 39509 S130 A S S D G S V S V L T C N T E
Honey Bee Apis mellifera XP_393516 311 34288 S129 G S S D G S V S I L I N N G D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788763 325 35667 S130 A S S D G S V S V L T H N D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04491 297 33025 L116 P H E Y G P L L L V A S S D G
Red Bread Mold Neurospora crassa Q7RZF5 304 33367 L121 P H E A G C L L A C A S S D G
Conservation
Percent
Protein Identity: 100 96.2 98.1 97.8 N.A. 96.8 97.1 N.A. 85.2 69.1 31.6 31 N.A. 51.4 64.9 N.A. 71.6
Protein Similarity: 100 97.1 98.1 98.7 N.A. 99 99 N.A. 91.6 71.9 48.8 49.1 N.A. 66.5 81 N.A. 87.3
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. 93.3 86.6 6.6 6.6 N.A. 53.3 53.3 N.A. 46.6
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 100 100 13.3 13.3 N.A. 73.3 80 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 49.6 48.1
Protein Similarity: N.A. N.A. N.A. N.A. 64.2 65.5
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 7 0 54 0 0 14 0 14 0 14 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 7 14 7 0 0 0 % C
% Asp: 0 0 0 74 0 0 0 0 0 0 0 0 0 34 14 % D
% Glu: 0 0 14 0 0 0 0 0 0 0 0 0 0 0 54 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 60 0 0 0 100 0 0 0 0 0 0 0 0 60 34 % G
% His: 0 14 14 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 54 0 7 0 7 0 0 0 0 % I
% Lys: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 14 14 27 60 74 0 0 0 0 0 % L
% Met: 0 0 0 14 0 0 14 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 7 20 0 0 % N
% Pro: 27 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 74 74 0 0 20 0 74 0 0 14 27 14 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 7 14 47 0 54 7 0 % T
% Val: 0 0 0 0 0 0 20 0 14 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 54 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _